Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2001-06-06
2008-11-04
Saucier, Sandra E. (Department: 1651)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C250S399000, C205S209000
Reexamination Certificate
active
07445885
ABSTRACT:
A process is described for analyzing enzyme-catalyzed conversions of nonpolymeric substrates to nonpolymeric products with the aid of MALDI-TOF mass spectrometry, preferably in the presence of an internal standard on a specific carrier material.
REFERENCES:
patent: 3948731 (1976-04-01), Weaver
patent: 5643800 (1997-07-01), Tarantino et al.
patent: 6824982 (2004-11-01), Reetz et al.
patent: 6897072 (2005-05-01), Rich et al.
patent: WO 58504 (2000-10-01), None
Whittman et al. “MALDI-TOF MS for Quantification of Substrates and Products in Cultivations ofCorynebacterium glutamicum” Biotechnol. Bioeng. (Feb. 2001) 76; 642-47.
Barnes et al. “Liquid Chromatography: Mass Spectroscopy of Isoflavones” J. Medicinal Food (1999) 2(3-4): 111-117.
Craig et al. “Monitoring protein kinase and phosphatase reactions with matrix-assisted laser desorption/ionization mass spectroscopy and capillary zone phosphopeptide mixtres” Biological Mass Spec. (1994) 23(8): 519-528.
Suh, et al., Application of capillary electrophoresis to determination of enzyme activity and other properties of phosphatidylinositol-specific phospholipase C, Journal of Chromatography A, 781, (1997), 263-270.
Zenobi, et al., Ion Formation in Maldi Mass Spectrometry, Mass Spectrometry Reviews, (1998), 17, 337-366.
Ens, et al., Properties of Matrix-assisted Laser Desorption. Measurements with a Time-to-Digital Converter, Rapid Communications in Mass Spectrometry, vol. 5, No. 3, (1991). p. 117-123.
Garden, et al., Heterogeneity within MALDI Samples as Revealed by Mass Spectrometric Imaging, Anal. Chem., (2000), 72, 30-36.
Cohen, et al., Influence of Matrix Conditions on the MALDI-MS Analysis of Peptides and Proteins, Anal. Chem, (1996), 31-37. vol. 68.
Strupat, et al., 2,5-Dihydroxybenzoic acid: a new matrix for laser desorption-ionization mass spectrometry, International Journal of Mass Spectrometry and Ion Processes, 111 (1991) 89-102.
Amado, et al., Discrimination Effects and Sensitivity Variations in Matrix-assisted Laser Desorption/Ionization, Rapid Communications in Mass Spectrometry, vol. 11, 1347-1352 (1997).
Gusev, et al., Improvement of Signal Reproducibility and Matrix/Comatrix Effects in MALDI Analysis, Anal. Chem. (1995), 67, 1034-1041.
Hensel, et al., Electrospray Sample Preparation for Improved Quantitation in Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry, Rapid Communications in Mass Spectrometry, vol. 11, 1985-1793 (1997).
Duncan, et al., Quantitative Analysis of Low Molecular Weight Compounds of Biological Interest by Matrix-assisted Laser Desorption Ionization; Rapid Communications in Mass Spectrometry, vol. 7, 1090-1094, (1993).
Goheen, et al., Mass Spectrometry of Low Molecular Mass Solids by Matrix-assisted Laser Desorption/Ionization, Journal of Mass Spectrometry, vol. 32, 820-828 (1997).
Bagree, et al., FEBS Letters, vol. 120, No. 2, (Nov. 1980), pp. 275-277.
Hauer Bernhard
Heinzle Elmar
Hollemeyer Klaus
Kang Min-Jung
Tholey Andreas
BASF - Aktiengesellschaft
Connolly Bove & Lodge & Hutz LLP
Hanley Susan
Saucier Sandra E.
LandOfFree
Method for analyzing enzyme-catalyzed reactions using... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for analyzing enzyme-catalyzed reactions using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for analyzing enzyme-catalyzed reactions using... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4040329