Method for analytically utilizing microfabricated sensors during

Chemistry: electrical and wave energy – Processes and products – Processes of treating materials by wave energy

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2041531, 20415317, 204403, 204400, 204402, 204406, G01N 2726, C25F 700

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active

051124556

ABSTRACT:
A method of determining the concentration of a preselected analyte species present in a sample fluid is disclosed, which method comprises: (a) providing an external computational means, a reference electrode and at least one substantially dry-stored sensor capable of exhibiting a response to changes in the concentration of a preselected analyte species before the sensor attains full equilibrated wet-up; (b) establishing electrical contact between the sensor, reference electrode and external computational means; (c) contacting the sensor and reference electrode with a calibrant fluid; (d) performing a first signal measurement in a first time window in the presence of the calibrant fluid; (e) displacing the calibrant fluid after performing the first signal measurement; (f) contacting the sensor and reference electrode with a sample fluid; (g) performing a second signal measurement in a second time window in the presence of the sample fluid; and (h) relating the first and second signal measurements to determine the concentration of the preselected analyte species in the sample fluid before said sensor attains full equilibrated wet-up. Alternative methods are disclosed further for collecting, relating and manipulating the results of the signal measurements to provide useful estimates of the analyte concentrations of interest.

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