Chemistry: analytical and immunological testing – Nitrogen containing – Amine and quaternary ammonium
Patent
1990-11-20
1993-05-18
Housel, James C.
Chemistry: analytical and immunological testing
Nitrogen containing
Amine and quaternary ammonium
436131, 436172, 436161, G01N 3300
Patent
active
052120970
ABSTRACT:
Catecholamines in a living body fluid are analyzed by a process which involves reacting a living body fluid sample with a boron compound of the formula: ##STR1## wherein R is hydroxyl, aryl or alkyl, to form a complex of the boron compound with a catecholamine; deproteinizing the reaction solution containing the complex; decomposing the complex to release the catecholamine; labeling the released catecholamine to form a labeled catecholamine; eluting the labeled catecholamine adsorbed on a separation column; and detecting the eluted, labeled catecholamine. Advantageously, this process enables catecholamines to be measured with a high recovery ratio and high accuracy by forming the catecholamines into a complex with a boron compound.
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Kamahori Masao
Miura Junkichi
Nogami Taro
Taki Mamoru
Watanabe Yoshio
Hitachi , Ltd.
Housel James C.
Tran Lien
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