Method for an increased visualization of the reaction product of

Details Method for an increased visualization of the reaction product of Method for an increased visualization of the reaction product of

1992-06-12

1994-09-20

Parr, Margaret

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

436524, 436164, 436805, 436 73, 252340, 2523152, 252302, G01N 33553, G01N 2100, B01D 1704, B01J 1300

Patent

active

053488911

ABSTRACT:
The invention herein is directed to a method for the visualization of the product of the reaction of a specifically binding substance and a corresponding bindable substance. The reaction product is formed during an assay procedure for the detection and/or determination of one of the components of the reaction. The assay involves the use of a component labeled by a sol of a non-metallic element, such as selenium and tellurium, and the use of a physical developer comprising a metal compound, such as silver lactate and silver nitrate, mercuric chloride and a copper sulfate, to strengthen or reinforce a specific signal, thereby improving detectability.

REFERENCES:
patent: 4954452 (1990-09-01), Yost et al.
patent: 5120643 (1992-06-01), Ching et al.
Weiser, H. B. Inorganic Colloid Chemistry, vol. 1 "The Colloidal Elements", 1933, pp. 305-360.

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