Method for amplification of targeted segments of nucleic acid us

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 6, 935 17, 935 77, 536 2432, 536 2433, C12P 1934, C12Q 168

Patent

active

053407288

ABSTRACT:
An improved method for performing a nested polymerase chain reaction (PCR) amplification of a targeted piece of DNA, wherein by controlling the annealing times and concentration of both the outer and the inner set of primers according to the method disclosed, highly specific and efficient amplification of a targeted piece of DNA can be achieved within one reaction vessel without depletion or removal of the outer primers from the reaction mixture vessel.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4965188 (1990-10-01), Mullis
patent: 5126239 (1992-06-01), Livak
Wu et al. DNA & Cell Biology 1991 10:233-238.
Wetmur, Crit Rev Biochem & Molec Biology, 1991 26:227-259.
Erlich et al Science (1991) 252:1643-1651.
Williams et al. Nucl Acid Res (1990) 18:6531-6535.
Simmonds et al J. Virol (1990) 64:864-872.
Lin et al J Med Virol (1992) 38:220-225.
U. Linz et al., J. Clim. Chem. Clin. Biochem. 28:5-13 (1990).
W. Rychlik et al., Nucl. Acids. Res., 18:6409-6412 (1990).
J. A. Garson et al., Lancet, 335:1419-1422 (1990).
K. Porter-Jordan et al., J. Med. Virol., 30:85-91 (1990).
E. Rimstad et al., J. Clin. Microbiol, 28(10):2275-2778 (1990).
D. Welch et al., Appl. Env. Microbiol., 56(8):2494-2498 (1990).
U. B. Gyllensten et al., Proc. Nat'. Acad. Sci., 85:7652-5656 91988).
Yourno, PCR Methods and Applications, 2:60-65 (1992).
R. J. Britten et al., Science 161(3841):529-540 (1968).
J. G. Wetmur, J. Mol. Biol. 31:349-370 (1968).
B. D. Young et al., Biochem. J. 135:573-576 (1973).
T. G. Wood et al., J. Biol. Chem., 252:457-463 (1977).
M. D. Olive, J. Clin. Microbiol., 27(2):261-265 (1989).
I. G. Wilson, Appl. Env. Microbiol. 57(6):1793-1798 (1991).
B. Furrer et al., J. Appl. Bact. 70:372-379 (1991).
C. Matsumoto et al., J. Virol, 64(11) 5290-5294 (Nov. 1990).
B. B. Plykaytis et al., J. Clin. Micro., 28(9):1913-1917 (Sep. 1990).
K. Wernars et al., J. App. Bact., 70:121-126 (1991).
K. A. Lampel., et al., Appl. Environ. Microbiol., 56:1536-1540 (Jun. 1990).
K. Wernars et al., Appl. Environ. Microbiol., 57(7):1914-1919 (Jul. 1991).
W. E. Hill et al., Appl. Environ. Microbiol., 57(3):707-711 (Mar. 1991).
U. Candrian et al., Int. J. Food Microbiol., 12(4):339-352 (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for amplification of targeted segments of nucleic acid us does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for amplification of targeted segments of nucleic acid us, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for amplification of targeted segments of nucleic acid us will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-502285

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.