Method for amino acid sequencing of protein or peptide from carb

Details Method for amino acid sequencing of protein or peptide from carb Method for amino acid sequencing of protein or peptide from carb

1997-05-23

2000-04-04

Weber, Jon P.

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

Amino acid or sequencing procedure

436 90, G01N 3350, G01N 3300

Patent

active

060460539

ABSTRACT:
A process is disclosed for sequencing proteins or peptides from the C-terminal end. The process comprises the steps of reacting the peptide or protein with an alkyl acid anhydride to convert the carboxy-terminal thereof into oxazolone, liberating the C-terminal amino acid by reaction with acid and alcohol or with ester, and identifying the liberated amino acid or amino acid derivative.

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