Method for altering red blood cell function and survival

Details Method for altering red blood cell function and survival Method for altering red blood cell function and survival

1983-08-08

1984-10-23

Rosen, Sam

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

A61K 3518

Patent

active

044788240

ABSTRACT:
Method and apparatus for creating reversible intracellular hypertonicity in red blood cells of mammals in order to introduce desired materials into the cells or achieve therapeutically desirable changes in the characteristics of intracellular hemoglobin. A packed red blood cell fraction is incubated in a solution containing a compound which readily diffuses into and out of the cells; a trans-membrane osmotic gradient is rapidly created by contacting the cells with a near-isotonic aqueous medium with or without a desired agent to be introduced, causing diffusion of water into the cells with consequent swelling thereof and permitting diffusion of said compound out of the cells; and the cells are then separated and washed to obtain a sterile fraction of substantially intact cells.

REFERENCES:
Parsons et al.-Chem. Abst., vol. 91 (1979), p. 68355d.
Zimmermann et al.-Chem. Abst., vol. 94 (1981), p. 90235y.
Zimmermann et al.-Chem. Abst., vol. 89 (1978), p. 135851m.
Zimmermann et al.-Chem. Abst., vol. 86 (1977), p. 34,228w.

Affiliated with

Also associated with

Rating

Method for altering red blood cell function and survival does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for altering red blood cell function and survival, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for altering red blood cell function and survival will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1598643