Method for alleviation of primary depressive disorders

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31505

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active

047710535

ABSTRACT:
Gepirone and its pharmaceutically acceptable salts are useful in alleviation of certain primary depressive disorders, such as major depression with melancholia and atypical depression.

REFERENCES:
patent: 4423049 (1983-12-01), Temple
"Annual Reports in Medicinal Chemistry", vol. 21, pp. 15,43 (3/3) (1986).
Eison et al., Iuphar. Abstract, (London): 2018 (1984) (3/8).
Eison et al., Neuroscience Abstract 10:259 (1984) (3/9).
Eison et al., Eur. J. Pharmacol., 111:389-392 (1985) (3/10).
Eison et al., Drugs of the Future, 10:456-457 (1985) (3/11).
Eison et al., Neuroscience Abstract, 11:186 (1985) (3/14).
Schweizer et al., Psychopharmacol. Bull., 22:183-185 (1986) (7/4).
"Open Trial of Gepirone in the Treatment of Major Depressive Disorder" by J. D. Amsterdam et al., Current Therapeutic Research, 41/2:185-194 (1987).

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