Gas separation: processes – Chromatography – With heating or cooling
Patent
1997-05-06
1998-12-08
Spitzer, Robert
Gas separation: processes
Chromatography
With heating or cooling
95 82, 73 2326, 73 2327, B01D 1508
Patent
active
058462937
ABSTRACT:
A method of admitting and receiving a sample into a gas chromatographic column is provided in which a step increase in pressure is performed in combination with the application of a negative axial thermal gradient to provide pre-separation of solutes in the sample within the inlet region of the column. The method includes the steps of introducing a sample into the column at a first pressure and temperature, rapidly raising the temperature to invoke a negative axial thermal gradient, and then substantially instantaneously increasing the pressure. The method causes the solutes in the sample to be partially separated into narrow zones within the inlet region, resulting in eventually achieving maximum resolution.
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Rubey Wayne A.
Striebich Richard C.
Spitzer Robert
The University of Dayton
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