Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1993-10-28
1995-07-11
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424484, 424486, 424487, 424489, A61K 928, A61K 926
Patent
active
054319226
ABSTRACT:
An improved method for administering buspirone comprises oral administration of controlled/extended release formulations of buspirone and salts thereof which require from about 6 to 24 hours for in vitro dissolution of at least 80% of the buspirone content. Administration of these formulations increases buspirone bioavailability in relation to its major metabolite. Improved efficacy, drug tolerability and patient convenience result from this improved method of administration.
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Bawa Raj
Bristol--Myers Squibb Company
Page Thurman K.
Ryan Richard P.
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