Method for administration of azauridine and pyridoxine for the t

Details Method for administration of azauridine and pyridoxine for the t Method for administration of azauridine and pyridoxine for the t

1993-11-12

1995-02-14

Henley, III, Raymond J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514332, 514825, 514922, A61K 3170, A61K 3144

Patent

active

053896173

ABSTRACT:
A method for treating patients with rheumatoid arthritis comprises administering azaribine to the patient at a dosage level of 10 to 50 mg/kg/day for an initial period of from about 1 to about 3 weeks and then administering azaribine to the patient at dosage levels of at least 50 mg/kg/day and preferably at least 100 mg/kg/day.

REFERENCES:
New Indications For 6-Azauridine Treatment In Man, by Elis and Raskova, Europ.J.Clin.Pharmacol. 4, 77-81 (1972).
Side Effects Of 67-Azauridine Triacetate In Rheumatoid Arthritis, by Elis, Slavik, Raskova, Clin.Pharmacol. & Therap., II., 404-407 (1970).
Unexpected Side Effects of 6-Azauridine In Rheumatoid Arthritis And Feedback In Animal Experiments, by Raskova, Elis, Perlik, Polansky and Slavik, Proc.Soc.Europ. for the Study of Drug Toxicity, Upsala, Jun. 1970, 12 191 (1971).
Chemical Abstracts 74:109871p (1971).
Chemical Abstracts 77:14345t (1977).

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