Surgery – Respiratory method or device – Respiratory gas supply means enters mouth or tracheotomy...
Patent
1992-03-26
1993-05-04
Burr, Edgar S.
Surgery
Respiratory method or device
Respiratory gas supply means enters mouth or tracheotomy...
12820312, 604 56, 604 93, A61M 1610, A61M 3100, A61M 1100, A62B 906
Patent
active
052072207
ABSTRACT:
A method of administering a liquid pharmaceutical formulation, particularly a surfactant formulation, to at least one lung of a subject in need of such treatment is disclosed. The method is carried out while the subject has a breathing tube extending through the subject's mouth and larynx, and while ventilating at least one lung of the subject through the breathing tube. The method comprises simultaneously administering the liquid pharmaceutical formulation down the breathing tube and into at least one lung of the subject and ventilating at least one lung of the subject through the breathing tube. The method may be performed on premature infants to combat respiratory distress syndrome. A preferred apparatus for carrying out the method of the present invention comprises a breathing tube configured for insertion through a subject's mouth and larynx, a ventilating apparatus operatively associated with the breathing tube, and an injecting device such as a syringe operatively associated with the breathing tube for introducing a liquid pharmaceutical formulation into the breathing tube.
REFERENCES:
patent: 4312860 (1982-01-01), Clements
patent: 4723543 (1988-02-01), Beran
patent: 4815459 (1989-03-01), Beran
patent: 4826821 (1989-05-01), Clements
patent: 4953547 (1990-09-01), Poole, Jr.
Wilkinson et al., The Lancet Ltd., 287-291, Aug. (1985).
Enhorning et al., Pediatrics 76, No. 2, 145-153 (1985).
Hallman et al., Pediatrics 71, 473-482 (1983).
Enhorning et al., American Review of Respiratory Disease, 107, 921-927 (1973).
Ferrara et al., Journal of Pediatric, "Localization of Surfactant in Neonatal Lung after . . . ", 1987, St. Louis, Mo.
Clinical Manifestations of Respiratory Disease, Jerry des Jardins, Ch. 13, pp. 312-326, Year Book Medical Publishers, .COPYRGT.1984.
Publication by Burroughs Wellcome Co. Entitled "Product Monograph. Synthetic Lung Surfactant for the Treatment of Neonatal Respiratory Distress Syndrome" (1990).
Pamphlet by Ross Laboratories on Survanta Beractant, Intratracheal Suspension (1991).
Videotape Recording showing the administration of Exosurf and Survanta.
T. Fujiwara et al., "Artificial Surfactant Therapy in Hyaline Membrane Disease," Lancet 1, 55 (1980).
J. Horbar et al., "A Multicenter Randomized, Placebo-Controlled Trial of Surfactant Therapy For Respiratory Distress Syndrome," N. Eng. J. Med. 320, 959 (1989).
R. Soll et al., "Multicenter Trial of Single Dose Surfactant-TA (STA) For Prevention of Respiratory Distress Syndrome (RDS)," Pediatric Res. 23, 425A (1988).
Y. Tanaka et al., "Development of Synthetic Lung Surfactants," Journal of Lipid Research 27, No. 2, 475 (1986).
Asher Kimberly L.
Burr Edgar S.
Burroughs Wellcome Co.
The Wellcome Foundation Ltd.
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