Method for administering a cytokine to the central nervous...

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Reexamination Certificate

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C424S085700, C424S085500, C424S085400, C424S085100, C514S002600, C530S351000, C530S350000, C530S399000

Reexamination Certificate

active

06991785

ABSTRACT:
The present invention is directed to a method for delivering cytokines to the central nervous system and the lymphatic system by way of a tissue innervated by the trigeminal nerve and/or olfactory nerve. Cytokines include tumor necrosis factors, interleukins, interferons, particularly interferon-β and its muteins such as IFN-βser17. Such a method of delivery can be useful in the treatment of central nervous system disorders, brain disorders, proliferative, viral, and/or autoimmune disorders such as Sjogren's disorder.

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