Method for accelerating skin wound healing with H3 protein

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 12, 514885, 514886, 514887, 514944, 514945, 514946, 514947, 424409, 4242781, A61K 910, C07K 1708

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055997880

ABSTRACT:
A method of producing recombinant transforming growth factor .beta.-induced H3 protein and the use of this protein to accelerate wound healing. H3 promoted adhesion of human dermal fibroblasts to tissue culture plastic. The protein is applied directly to a wound or is used to promote adhesion and spreading of dermal fibroblasts to a solid support such as a nylon mesh which is then applied to the wound. In addition, CHO cells expressing H3 inhibited tumor cell growth.

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