Method for accelerating clearance of hemorrhagic blood from the

Details Method for accelerating clearance of hemorrhagic blood from the Method for accelerating clearance of hemorrhagic blood from the

1995-11-22

1999-02-02

Naff, David M.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424 941, 514 2, 514912, 435201, A61K 3843, A61K 3846, C12N 926

Patent

active

058661204

ABSTRACT:
A thimerosal-free hyaluronidase preparation wherein the preferred hyaluronidase enzyme is devoid of molecular weight fractions below 40,000 MW, between 60-70,000 MW and above 100,000 MW. Also disclosed is a method for accelerating the clearance of hemorrhagic blood from the vitreous humor of the eye, comprising the step of contacting at least one hemorrhage-clearing enzyme (e.g., a .beta.-glucuronidase, matrix metalloproteinase, chondroitinase, chondroitin sulfatase or protein kinase) with the vitreous humor in an amount which is effective to cause accelerated clearance of blood therefrom.

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