Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-05-16
2006-05-16
Desai, Rita (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C548S542000
Reexamination Certificate
active
07045629
ABSTRACT:
The present invention relates to a process for the preparation of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, the enantiomers and its salts, characterised in that 5-(4-fluorophenyl)pyridine-3-carbaldehyde is reacted directly with aminomethylchroman or its salts under reducing conditions to give 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]chroman, and the latter is, if desired, converted into one of its physiologically acceptable salts by treatment with an acid.
REFERENCES:
patent: 5318988 (1994-06-01), Schohe-Loop et al.
patent: 5767132 (1998-06-01), Boettcher et al.
patent: 10005150 (2001-08-01), None
patent: 2701479 (1994-08-01), None
patent: WO 9418193 (1994-08-01), None
patent: WO 0158873 (2001-08-01), None
Baraldi et al, “Resolution of A CPzl Precursor, synthesis and Biological Evaluation of (+) and (-) -N-Boc-CPzl”, Bioorganic and Medicinal Chemistry letters 9 (1999) 3087-3092.
Bokel Heinz-Hermann
Devant Ralf
Gantzert Ludwig
Helm Udo
Knierieme Ralf
Covington Raymond
Desai Rita
Merck Patent GmbH
Millen White Zelano & Branigan P.C.
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