Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2011-04-26
2011-04-26
Lu, Frank W (Department: 1634)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C435S006120, C435S091100, C435S091510, C536S023100, C536S024300, C536S024330, C536S025300
Reexamination Certificate
active
07932061
ABSTRACT:
This invention relates to the use of tumor-derived or associated extracellular ribonucleic acid (RNA) found circulating in the plasma or serum fraction of blood for the detection, monitoring, or evaluation of cancer or premalignant conditions. Specifically, this invention enables the extraction of circulating RNA from plasma or serum and utilizes nucleic acid amplification assays for the identification, detection, inference, monitoring, or evaluation of any neoplasm, benign, premalignant, or malignant, in humans or other animals, which might be associated with that RNA. Further, this invention allows the qualitative or quantitative detection of tumor-derived or associated extracellular RNA circulating in the plasma or serum of humans or animals with or without any prior knowledge of the presence of cancer or premalignant tissue.
REFERENCES:
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4699877 (1987-10-01), Cline et al.
patent: 4874858 (1989-10-01), Magistro
patent: 4999290 (1991-03-01), Lee
patent: 5019243 (1991-05-01), McEwen et al.
patent: 5087617 (1992-02-01), Smith
patent: 5098890 (1992-03-01), Gerwitz et al.
patent: 5124246 (1992-06-01), Urdea et al.
patent: 5155018 (1992-10-01), Gillespie et al.
patent: 5217889 (1993-06-01), Roninson et al.
patent: 5274087 (1993-12-01), Barnett et al.
patent: 5300635 (1994-04-01), Macfarlane
patent: 5409818 (1995-04-01), Davey et al.
patent: 5470724 (1995-11-01), Ahern
patent: 6329179 (2001-12-01), Kopreski
patent: 6607898 (2003-08-01), Kopreski et al.
patent: 6759217 (2004-07-01), Kopreski
patent: 6794135 (2004-09-01), Kopreski et al.
patent: 6916634 (2005-07-01), Kopreski
patent: 3717212 DE (2003-09-01), None
patent: WO 90/09456 (1990-08-01), None
patent: 97/35589 (1997-10-01), None
patent: 98/14617 (1997-10-01), None
Rykova et al., Concentrations of Circulating RNA from Healthy Donors and Cancer Patients Estimated by Different Methods. Ann. N.Y. Acad. Sci., 1075, 328-333, 2006.
Ng et al., mRNA of placental origin is readily detectable in maternal plasma. PNAS, 100, 4748-4753, Apr. 15, 2003.
The definition for “Myc” from Wikipedia, the free encyclopedia. Printed on Sep. 15, 2008.
Ng et al., Evaluation of Human Chorionic Gonadotropin β-Subunit mRNA Concentrations in Maternal Serum in Aneuploid Pregnancies: A Feasibility Study. Clinical Chemistry, 50, 1055-1057, 2004.
Abravaya et al., “Detection of point mutations with a modified ligase chain reaction (GAP-LCR),”Nucleic Acids Research23:675-682 (1995).
Alkema et al., “Characterization and Chromosamal Localization of the Human Prata-Oncogene BMI-1,”Human Mol Genet2:1597-1603 (1993).
Aoki et al., “Liposome-mediated in viva gene transfer on antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity,”Cancer Research55:3810-3816 (1995).
Barz et al., “Characterization of Cellular and Extracellular Plasma Membrane Vesicles from a Non-metastasing Lymphoma (Eb) and Its Metastasing Variant (Esb),”Biochin Biophys Acta814:77-84 (1985).
Bauer et al., “Identification of H-2Kb Binding and Immunogenic Peptides from Human Papillama Virus Tumour Antigens E6 and E7,”Scand J Immunol42:317-323 (1995).
Blackburn et al., “Electrochemiluminescence detection for development of immunoassays and DNA probe assays for clinical diagnostics,”Olin Chem37/9:1534-1539 (1991).
Bobo et al., “Diagnosis of chlamydia trachomatis cervical infection by detection of amplified DNA with an enzyme immunoassay,”J din Micra28:1968-1973 (1990).
Bocchia et al., “Specific Binding of Leukemia Oncogene Fusion Peptides to HLA Class I Molecules,”Blood85:2680-2684 (1995).
Boom et al., “Rapid and Simple Method for Purification of Nucleic Acids,”J Clin Micro28:495-503 (1990).
Boom et al., “Rapid Purification of Hepatitis B Virus DNA from Seruc,”J Clin Micro29:180-181 (1991).
Brossart et al., “Detection of residual tumor cells in patients with malignant melanoma responding to immunotherapy,”J Immunotherapy15:38-41 (1994.
Buchman et al., “Selective RNA amplification: A novel method using d UMP-containing primers and uracil DNA glycosylase,”PCR Methods Applic3:28-31 (1993).
Carr et al., “Circulating Membrane Vesicles in Leukemic Blood,”Cancer Research45:5944-5951 (1985).
Cheung et al., “Rapid and Sensitive Method for Detection of Hepatitis C Virus RNA by Using Silica Particles,”J Clin Micro32:2593-2597 (1994).
Chirgwin et al., “Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease,”Biochemistry18:5294-5299 (1979).
Chomczynski and Mackey, “Modification of the TRI reagent (TM) procedure for isolation of RNA from polysaccaride- and proteaglycan-rich sources,”BioTechniques19:942-945 (1995).
Chomczynski and Mackey, “Substitution of chloroform by bromo-chloropropane in the single-step method of RNA isolation,”Analytical Biochemistry225:163-164 (1995).
Chomczynski et al., “Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction,”Analytical Biochemistry162:156-159 (1987).
Chomczynski, “A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples,”Biotech15:532-537 (1993).
Chu et al., “Thymidylate synthase binds to c-myc RNA in human colon cancer cells and in vitro,”Mol Cell Biol15:179-185 (1995).
Cohen, “Biochemical Therapy: Antisense Compounds,”In: Biologic Teraphy of Cancer(DeVita, Hellman, Rosenberg, eds) J.B. Lippincott, Ca., Philadelphia (1991) pp. 763-775.
Colomer et al., “erB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erb-2 oncogene amplification,”Br J Cancer70:819-825 (1994).
Coutlee et al., “Immunodetection of DNA with biotinylated RNA probes: A study of reactivity of a monoclonal antibody to DNA-RNA hybrids,”Analytical Biochemistry181:96-105 (1989).
Datta et al., “Sensitive Detection of Occult Breast Cancer by the Reverse-transcriptase Polymerase Chain Reaction,”Journal of Clinical Oncology12:475-482 (1994).
Davidova and Shapot, “Liporibonucleoprotein Complex as an Integral Part of Animal Cell Plasma Membranes,”FEBS Lett6:349-351 (1970).
DiCesare et al., “A high-sensitivity electrochemiluminescense-based detection system for automated PCR product quantitation,”BioTechniques15:152-157 (1993).
Doi et al., “Detection of beta-human chorionic ganadotropin mRNA as a marker for cutaneoud malignant melanoma,”Int J Cancer65:454-45- (1996).
Dosaka et al., “A complex pattern of translational initiation and phosphorylation in L-Myc Proteins,”Oncogene6:371-378 (1991).
Edmands et al., “Rapid RT-PCR Amplification from Limited Cell Numbers,”PCR Methods Applic3:317-319 (1994).
Feng et al., “The RNA component of human telomerase,”Science269:1236-1241 (1995).
Fournie et al., “Recovery of nanogram quantities of DNA from plasma and quantitative measurement using labeling by nick translation,”Analytical Biochemistry158:250-256 (1986).
Gerhard et al., “Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction,”J Clin Oncol12:725-729 (1994).
Ghossein et al., “Detection of Circulating Tumor Cells in Patients with Localized and Metastatic Prostatic Carcinoma: Clinical Implications,”Journal of Clinical Oncology13:1195-1200 (1995).
Higashiyama et al., “Reduced Motility Related Protein-1 (MRP-1/CD9) Gene Expression as a Factor of Poor Prognosis in Non-small Cell Lung Cancer,”Cancer Research55:6040-6044 (1995).
Hoon et al., “Detection of occult melanoma cells in blood with a multiple-marker polymerase chain reaction assay,”J Clin Oncol13:2109-2116 (1995).
Hoover et al., “Immunatherapy by Active
Lu Frank W
McDonnell & Boehnen Hulbert & Berghoff
OncoMEDx, Inc.
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