Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...
Patent
1997-03-13
1998-09-08
Ketter, James
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
435357, 4353201, 4352851, C12N 704
Patent
active
058044310
ABSTRACT:
This invention provides methods, compositions and apparatus for increasing the transfection efficiency of target cells by particles, especially retroviral particles, compared with that achieved by current methods. The transfection method comprises depositing the particles on a cell growth support and contacting target cells with the particle-loaded cell growth support.
REFERENCES:
patent: 1316789 (1919-09-01), Grimwood et al.
patent: 3839155 (1974-10-01), McAleer et al.
patent: 4159933 (1979-07-01), Allington et al.
patent: 4164464 (1979-08-01), Allington et al.
patent: 4201845 (1980-05-01), Feder et al.
patent: 4301010 (1981-11-01), Eddleman et al.
patent: 4339537 (1982-07-01), Sogi et al.
patent: 4632761 (1986-12-01), Bowers et al.
patent: 5139951 (1992-08-01), Butz et al.
patent: 5260211 (1993-11-01), Matsuda et al.
Russell, Stephen J. et al., "Retroviral Vectors Displaying Functional Antibody Fragments." Nucleic Acids Res. 21:1081-1085 (1993).
Grass, George M. and Sweetana, Stephanie A. "In Vitro Measurement of Gastrointestinal Tissue Permability Using a New Diffusion Cell." Pharma. Res. 5:372-376 (1988).
The Controlled Environment Incubator Shaker, New Brunswick Scientific Co. Catolog (1966) p. 1-8.
Krieger, Michael, Gene Transfer and Expression W.H. Freeman and Company, New York, New York. pp. 1-242.
Cornetta, Kenneth and Anderson, W. French., "Protamine Sulfate as an Effective Alternative to Polybrene in Retroviral-Mediated Gene-Transfer: Implications for Human Gene Therapy." J. Virol Methods. 23:187-194.
Paul, Ralph W. et al., "Increased Viral Titer Through Concentration of Virol Harvests from Retroviral Packaging Lines." Human Gene Ther. 4:609-615 (1993).
Bodine, David M. et al., "Development of a High-titer Retrovirus Producer Cell Line Capable of Gene Transfer into Rhesus Monkey Hematopoietic Stem Cells." Proc. Natl. Acad. Sci. USA. 87:3738-3742 (1990).
Kaufman, Randal J. "Vectors Used for Expression in Mammalian Cells." Meth. Enzy. 185:487-537 (1990).
Cussler, E.L. Dissfusion, Mass Transfer in Fluid Systems. Cambridge University Press, Cambridge pp. 75-78 (1987).
Cassel, Aliza et al., "Retroviral-mediated Gene Transfer into CD34-Enriched Human Peripheral Blood Stem Cells." Exper. Hema. 21:585-591 (1993).
Palsson, B. Activation, Metabolism and Perfusion of the Heart. Sideman, S. and Beyar, R. (editors) Martinus Nijhoff Publishers. Boston, Mass. 585-620 (1987).
Hidalgo, Ismael J. et al., "Characterization of the Unstirred Water Layer in Caco-2 Cell Monolayers Using a Novel Diffusion Apparatus." Pharma. Res. 8:222-227 (1991).
Mulligan, Richard C. "The Basic Science of Gene Therapy." Science 260:926-932 (1993).
Bluestone, Mimi, "Genes in a Bottle." Bio/Technology 10:132-136 (1992).
Langer, Robert and Vacanti, Joseph P., "Tissue Engineering." Science 260:920-926 (1993).
Verma, Inder M., "Gene Therapy." Sci. Amer. 77-84 (1990).
Krauss, John C., "Hematopoietic Stem Cell Gene Replacement Therapy." Biochimica et Biophysica Acta. 1114:193-207 (1992).
Kotani, Hitoshi et al., "Improved Methods of Retroviral Vector Transduction and Production of Gene Therapy." Human Gene Ther. 5:19-28 (1994).
Lynch, Carmel M. and Miller, A. Dusty "Production of High-Titer Helper Virus-Free Retroviral Vectors by Cocultivation of Packaging Cells with Different Host Ranges." J. Virol. 65:3887-3890 (1991).
Morgan, Jeffrey R. et al., "Advances in Recombinant Retrovirus for Gene Delivery." Advances. Drug Develop. Review. 12:143-158 (1993).
Keown, Wayne A. et al., "Methods for Introducing DNA into Mammalian Cells." Methods in Enzy. 185:527-537 (1990).
Davison, Andrew J. and Elliot, Richard M. Molecular Virology, A Practical Approach. IRL Press, New York, New York, Chptr. 6, 171-197 (1992).
Ketter James
The Regents of the University of Michigan
Yucel Irem
LandOfFree
Method, compositions and apparatus for cell transfection does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method, compositions and apparatus for cell transfection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method, compositions and apparatus for cell transfection will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1281265