Image analysis – Applications – Biomedical applications
Reexamination Certificate
2007-10-09
2007-10-09
Desire, Gregory M (Department: 2624)
Image analysis
Applications
Biomedical applications
C378S021000, C378S054000, C378S064000, C382S131000, C382S199000, C382S259000, C600S407000
Reexamination Certificate
active
10625444
ABSTRACT:
A method, machine-readable storage medium embodying computer-readable code and automated system for assaying or monitoring the extent of joint or bone deformity reported by a summarized score that may include joint space narrowing, bone erosion and periarticular osteoporosis in a joint-degenerative or joint-damaging disease in a subject are disclosed. From a digitized image of one of the subject's straight bone terminated with a joint such as fingers, coordinates of right and left bone contours of a selected middle or proximal phalange are determined, and these coordinates are in turn used to determine the coordinates of a minimum width in the middle region of the phalange and one or more apices in a region adjacent at least one side of a joint of the selected phalange. These latter coordinates are used in selecting a reference joint contour representing normal-bone contour for that phalange, or the contour of the patient phalange from an earlier x-ray image. Guided by the reference joint contour, a region of the selected joint of the patient is analyzed to assay or monitor the extent of joint or bone deformity in the subject.
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Bi Xiaoli
Shim Joon
Compumed, Inc.
Desire Gregory M
Perkins Coie LLP
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