Surgery – Diagnostic testing – Cardiovascular
Reexamination Certificate
2003-09-18
2009-11-24
Manuel, George (Department: 3762)
Surgery
Diagnostic testing
Cardiovascular
Reexamination Certificate
active
07623912
ABSTRACT:
A method of determining sleep stages from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs. The method comprising: (a) extracting a series of cardiac R-R intervals from the signals and obtaining a time-frequency decomposition from the series of cardiac R-R intervals; (b) using the time-frequency decomposition to determine at least one Slow-Wave-Sleep (SWS) period and at least one Non-SWS (NSWS) period; (c) from the at least one NSWS period, determining at least one sleep-onset (SO) period and a plurality of non-sleep periods; (d) extracting a plurality of electromyogram (EMG) parameters from a portion of the signals, the portion corresponds to a NSWS period other than the at least one SO period and other than the plurality of non-sleep period; (e) using the plurality of EMG parameters to determine at least one REM period thereby also to obtain also at least one light-sleep (LS) period defined as a NSWS period other than the SO periods, other than the non-sleep periods and other than the REM periods; thereby determining the sleep stages of the sleeping subject.
REFERENCES:
patent: 5265617 (1993-11-01), Verrier et al.
patent: 5797840 (1998-08-01), Akselrod et al.
patent: 5902250 (1999-05-01), Verrier et al.
patent: 2004/0073098 (2004-04-01), Geva et al.
patent: 2006/0235315 (2006-10-01), Akselrod et al.
patent: WO 2004/026133 (2004-04-01), None
Shinar et al. “Automatic Detection of Slow-Wave-Sleep Using Heart Rate Variability”, Computers in Cardiology, 28: 593-596, 2001.
Official Action Dated Oct. 2, 2008 From the US Patent Office Re.: U.S. Appl. No. 10/528,456.
Baharav et al. “Fluctuations in Autonomic Nervous Activity During Sleep Displayed by Power Spectrum Analysis of Heart Rate Variability”, Neurology, 45(6): 1183-1187, 1995. Abstract.
Berlad et al. “Power Spectrum Analysis and Heart Rate Variability in Stage 4 and REM Sleep: Evidence for State-Specific Changes in Autonomic Dominance”, Journal of Sleep Research, 2(2): 88-90, 1993. Abstract.
Bonnet et al. “Heart Rate Variability: Sleep Stage, Time of Night, and Arousal Influences”, Electroencephalography and Clinical Neurophysiology, 102: 390-396, 1997.
Monti et al. “Autonomic Control of the Cardiovascular System During Sleep in Normal Subjects”, European Journal of Applied Physiology, 87: 174-181, 2002.
Penzel et al. “Systematic Comparison of Different Algorithms for Apnoea Detection Based on Electrocardiogram Recordings”, Medical & Biological Engineering & Computing, 40: 402-407, 2002.
Scholz et al. “Vegetative Background of Sleep: Spectral Analysis of the Heart Rate Variability”, Physiology & Behavior, 62(5): 1037-1043, 1997.
Shinar et al. “Autonomic Changes During Wake-Sleep Transition: A Heart Rate Variability Based Approach”, Autonomic Neuroscience: Basic and Clinical, 11P., 2006.
Shinar et al. “R Wave Duration as A Measure of Body Position Changes During Sleep”, Computers in Cardiology, 26: 49-52, 1999.
Van De Borne et al. “Effects of Wake and Sleep Stages on the 24-h Autonomic Control of Blood Pressure and Heart Rate in Recumbent Men”, American Journal of Physiology, Heart Circulation Physiology, 266(35): H548-H554, 1994.
Akselrod Solange
Baharav Armanda Lia
Shinar Zvika
Manuel George
Ramot At Tel Aviv University Ltd.
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