Method, apparatus, and article of manufacture for enhanced inter

Details Method, apparatus, and article of manufacture for enhanced inter Method, apparatus, and article of manufacture for enhanced inter

1997-09-17

2000-08-29

Wachsman, Hal

Data processing: measuring, calibrating, or testing

Calibration or correction system

702 66, 702111, 702191, 702193, 73 2323, G01N 3086

Patent

active

061121614

ABSTRACT:
A method, apparatus, and article of manufacture for enhanced integration of signals, such as those generated by chromatographs. In one embodiment an approximate baseline used for integration of a signal is improved to reduce error. Alternate embodiments filter drift, noise, or both from a signal prior to integration or simulated distillation. The signals are processed according to a computer program stored in a memory. The methods include steps for subtracting an approximate baseline from the signal, defining a noise band in the resulting difference, and forming a composite baseline by substituting signal data for baseline data wherever the difference does not exceed the threshold, thus leaving the parts of the approximate baseline that correspond to signal peaks unchanged.

REFERENCES:
patent: 3555260 (1971-01-01), Karohl
patent: 4170893 (1979-10-01), Kleiss
patent: 4802102 (1989-01-01), Lacey
patent: 4837726 (1989-06-01), Hunkapiller
patent: 4941101 (1990-07-01), Crilly
patent: 5592402 (1997-01-01), Beebe et al.

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