Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1992-12-28
1994-09-27
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514523, 424687, A61K 3114, A61K 3310
Patent
active
053507711
ABSTRACT:
Hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitamin D. The hypotensive effect of this combination is synergistic and the dose response is more predictable than the administration of any of these agents singly.
REFERENCES:
patent: 3975539 (1976-08-01), Koppe et al.
patent: 4402872 (1983-09-01), Bohn
patent: 4443549 (1984-04-01), Sadowski
patent: 4621093 (1986-11-01), Ulrich et al.
patent: 4703038 (1987-10-01), Garthoff et al.
patent: 4837171 (1989-06-01), Codington
patent: 4855300 (1989-08-01), Nandi et al.
patent: 4859665 (1989-08-01), Garthoff et al.
patent: 4906647 (1990-03-01), Kouchiwa et al.
patent: 5047235 (1991-09-01), Lossnitzer et al.
Matsumura et al., The Journal of Pharmacology, vol. 241, No. 3, Jun., 1987, pp. 1000-1005.
Resnick et al., Federation Proceedings, vol. 45, No. 12, Nov., 1986, pp. 2739-2745.
Baran et al., The Journal of Clinical Investigation, vol. 77, No. 5, May, 1986, pp. 1622-1626.
Inoue et al., Biochemical and Biophysical Research Communications, vol. 152, No. 3, May 16, 1988, pp. 1388-1394.
Kotchen et al., The American Journal of Cardiology, vol. 62, Oct. 5, 1988, pp. 41-46.
Park et al., American Journal of Physiology, Index to vol. 240, 1981, pp. 70-74.
Glick et al., Anal. Chem., vol. 60, 1988, pp. 1982-1984.
Reichstein et al., Anal. Chem., 1988, vol. 60, pp. 1069-1074.
Dixon et al., Enzymes, Third Edition 1979, pp. 35-37.
Geiger et al., Chemical Abstracts, vol. 109, No. 143278b, 1988.
Luft et al., Chemical Abstracts, vol. 110, No. 128289h, 1989.
Park et al., The American Physiological Society, pp. F22-F25, 1978.
Bukoski et al., Biochemical and Biophysical Research Communications, vol. 146, No. 3, pp. 1330-1335, Aug. 14, 1987.
Benishin Christine G.
Lewanczuk Richard Z.
Pang Peter K. T.
Cintins Marianne M.
Criares T. J.
Pang Peter K. T.
LandOfFree
Method and treatment for hypertension using combination therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and treatment for hypertension using combination therapy , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and treatment for hypertension using combination therapy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1265787