Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Reexamination Certificate
2005-06-07
2005-06-07
Stucker, Jeffrey (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
C435S007100, C435S007920, C435S007940, C435S007950, C435S215000, C435S974000, C435S975000, C436S531000
Reexamination Certificate
active
06902884
ABSTRACT:
Method of diagnosing and/or prognosticating HIV infection in a subject comprising the steps of: (a) performing in vitro a measurement of the level of a marker in the form of (i) urokinase plasminogen activator receptor (uPAR), (ii) soluble urokinase plasminogen activator receptor (suPAR), (iii) urokinase-type plasminogen activator (uPA), (iv) one or more degradation products of (i), (ii), or (iii), and/or (v) an mRNA for (i), (ii) or (iii), in a biological fluid sample from a subject, and (b) using the measurement value obtained to evaluate the state of the subject.
REFERENCES:
patent: 4845026 (1989-07-01), Kung et al.
patent: 5459078 (1995-10-01), Kline et al.
patent: WO-01/38871 (2001-05-01), None
patent: WO-02/095411 (2002-11-01), None
Stephens et al. Clinical Chemistry vol. 43, No. 10 (1997), pp. 1868-1876.
Hengge et al. AIDS Vo. 12 (1998), pp. F225-F234.
Dekkers, Pascale E.P., et al., “Upregulation of Monocyte Urokinase plasminogen Activator Receptor during Human Endotoxemia”, Infection and Immunity, vol. 68, No. 4, Apr. 2000, pp. 2156-2160.
Coleman, James L., et al., “Borrelia burgdorferiand Other Bacterial Products Induce Expression and Release of the Urokinase Receptor (CD87)1”, The Journal of Immunology, vol. 166, 2001, pp. 473-480.
Florquin, et al., “Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia”, Kidney International, vol. 59, 2001, pp. 2054-2061.
Fauser, Susanne, et al., “Lesion associated expression of urokinase-type plasminogen activator receptor (uPAR, CD87) in human cerebral malaria”, Journal of Neuroimmunology, vol. 111, 2000, pp. 234-240.
Heegaard, C.W., et al., “Plasminogen Activators in Bovine Milk During Mastitis, an Inflammatory Disease”, Fibrinolysis, vol. 8, 194, pp. 22-30.
Todd, Robert, F., et al., “Bacterial lipopolysaccharide, phorbol myristate acetate, and muramyl dipeptide stimulate the expression of a human monocyte surface antigen”, The Journal of Immunology, vol. 135, No. 6, Dec. 1985, pp. 3869-3877.
Eugen-Olsen, J., et al., “The serum level of soluble urokinase receptor is elevated in tuberculosis patients and predicts mortality during treatment: a community study from Guinea-Bissau” Int. J. Tuberc. Lung Dis., vol. 6, No. 8, 2002, pp. 686-692.
Juffermans, Nicole P., et al., “Concurrent Upregulation of Urokinase Plasminogen Activator Receptor and CD11b during Tuberculosis and Experimental Endotoxemia”, Infection and Immunity, vol. 69, No. 8, 2001, pp. 5182-5185.
Garcia-Monco, Juan Carlos, et al., “Soluble urokinase receptor (uPAR, CD87) is present in serum and cerebrospinal fluid in patients with neurologic diseases”, Journal of Neuroimmunology, vol. 129, 2002, pp. 216-223.
Oct. 1, 2002 International Search Report issued during prosecution of PCT/DK02/00341.
Anders Nykjaer et al., “Urokinase Receptor, An Activation Antigen in Human T Lymphocytes,” Journal of Immunology, 1994, vol. 152, pp. 505-516.
Cornelia Speth et al., “Urokinase Plasminogen Activator Receptor (uPAR; CD87) Expression on Moncytic Cells and T Cells is Modulated by HIV-1 Infection,” Immunobiology, 1998, vol. 199, pp. 152-162.
Satu Mustjoki et al., “Soluble Urokinase Receptor Levels Correlate with Number of Circulating Tumor Cells in Acute Myeloid Leukemia and Decrease Rapidity during Chemotherapy,” Cancer Research, Dec. 15, 2000, vol. 60, pp. 7126-7132.
Sun Young Rha et al., “Correlation of tissue and blood plasmingen activation system in breast cancer,” Cancer Letters, 2000, vol. 150, pp. 137-145.
Darby & Darby
Stucker Jeffrey
Virogates ApS
LandOfFree
Method and tool for prognosticating HIV infection in a... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and tool for prognosticating HIV infection in a..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and tool for prognosticating HIV infection in a... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3500963