Method and system for suppressing bindings on magnetic...

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic

Reexamination Certificate

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Reexamination Certificate

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08053250

ABSTRACT:
A method for suppressing non-specific bindings between molecules includes providing magnetic particles dispersed in a liquid, wherein each of the magnetic particles has a magnetization. The magnetic particles are coated with coating molecules. Binding molecules mixed of first-type binding molecules and second-type binding molecules are applied to the liquid, wherein the coating molecules are specifically binding with the first-type binding molecules and non-specifically binding with the second-type binding molecules. An alternating current (ac) magnetic field is applied at an axis with a frequency level, wherein the frequency level causes suppression of the second-type binding molecules in binding with the coating molecules.

REFERENCES:
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patent: 2002/0009759 (2002-01-01), Terstappen et al.
patent: 2006/0205093 (2006-09-01), Prins
patent: WO 03/019188 (2003-03-01), None
patent: WO 2005/010527 (2005-02-01), None
J. Roger et al., “Some biomedical applications of ferrofluids” The European Physical Journal Applied Physics, Mar. 1, 1999, vol. 5, No. 3, pp. 321-325.
European Search Report of European Application No. 09251627.7—2204, dated Sep. 21, 2009.

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