Method and system for non-invasive detection of zinc protoporphy

Details Method and system for non-invasive detection of zinc protoporphy Method and system for non-invasive detection of zinc protoporphy

1979-01-03

1979-12-18

Cohen, Lee S.

Surgery

Truss

Pad

356 39, 356317, 128633, A61B 500

Patent

active

041789172

ABSTRACT:
A method and system for the non-invasive detection of zinc protoporphyrin (ZPP) in erythrocytes. Light at least partially within the fluorescence excitation spectrum of ZPP is directed onto the skin of a patient. The resultant incident light reflection and ZPP fluorescence from the region underlying the irradiated skin are detected. Signals representative of the detected light are generated and combined to provide a signal representative of the ZPP concentration in the erythrocytes within the sample region.

REFERENCES:
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patent: 3463142 (1969-08-01), Harte
patent: 3638640 (1972-02-01), Shaw
patent: 3811777 (1974-05-01), Chance
patent: 3825342 (1974-07-01), Lubbers et al.
patent: 4029085 (1977-06-01), DeWitt et al.
Blumberg et al, "The Hematofluorometer", Clinical Chemistry, vol. 23, No. 2, 1977.
Kobayashi et al, "Microfluorometry . . . In Situ," J. Applied Physiology, vol. 31, No. 5, Nov. 1971.
Shapiro et al, "Continuous Redox State . . . Organs," 26th, ACEMB, Minneapolis, Minn., Sep., 1973.

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