Method and system for myocardial infarction repair

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

Reexamination Certificate

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C607S003000, C600S016000, C424S093100

Reexamination Certificate

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07155288

ABSTRACT:
An implantable system is provided that includes: a cell repopulation source comprising genetic material, undifferentiated and/or differentiated contractile cells, or a combination thereof capable of forming new contractile tissue in and/or near an infarct zone of a patient's myocardium; and an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the infarct zone of the patient's myocardium or otherwise damaged or diseased myocardial tissue.

REFERENCES:
patent: 4256115 (1981-03-01), Bilitch
patent: 4379459 (1983-04-01), Stein
patent: 4411268 (1983-10-01), Cox
patent: 4476868 (1984-10-01), Thompson
patent: 4556063 (1985-12-01), Thompson et al.
patent: 4791911 (1988-12-01), Magovern
patent: 4821723 (1989-04-01), Baker et al.
patent: 5030204 (1991-07-01), Badger et al.
patent: 5060660 (1991-10-01), Gambale et al.
patent: 5069680 (1991-12-01), Grandjean
patent: 5104393 (1992-04-01), Isner et al.
patent: 5131388 (1992-07-01), Pless
patent: 5144949 (1992-09-01), Olson
patent: 5158078 (1992-10-01), Bennett et al.
patent: 5205810 (1993-04-01), Guiraudon et al.
patent: 5207218 (1993-05-01), Carpentier et al.
patent: 5243977 (1993-09-01), Trabucco et al.
patent: 5251621 (1993-10-01), Collins
patent: 5306293 (1994-04-01), Zacouto
patent: 5312453 (1994-05-01), Shelton et al.
patent: 5314430 (1994-05-01), Bardy
patent: 5354316 (1994-10-01), Keimel
patent: 5510077 (1996-04-01), Dinh et al.
patent: 5545186 (1996-08-01), Olson et al.
patent: 5632716 (1997-05-01), Bui et al.
patent: 5658237 (1997-08-01), Francischelli
patent: 5697884 (1997-12-01), Francischelli et al.
patent: 5807556 (1998-09-01), Mannion et al.
patent: 6151525 (2000-11-01), Soykan et al.
patent: 6671558 (2003-12-01), Soykan et al.
patent: 6775574 (2004-08-01), Soykan et al.
patent: 7031775 (2006-04-01), Soykan et al.
patent: 2006/0057693 (2006-03-01), Simon
patent: 0 487429 (1992-05-01), None
patent: 0 487429 (1992-05-01), None
patent: 0 547733 (1993-06-01), None
patent: 0 547733 (1993-06-01), None
patent: 0 627237 (1994-12-01), None
patent: WO 93/04724 (1993-03-01), None
patent: WO 94/11506 (1994-05-01), None
patent: WO 94/21237 (1994-09-01), None
patent: WO 95/05781 (1995-03-01), None
patent: WO 97/09088 (1997-03-01), None
patent: WO 99/66036 (1999-12-01), None
patent: WO 02/20088 (2002-03-01), None
Acsadi, et al., Direct Gene Transfer and Expression into Rat Heart In-Vivo, The New Biologist, 3(1):71-81, 1991.
Bansal, et al., Calclum-Regulated Secretion of Tissue Plasmnogen Activator and Parathyroil Hormone from Human Parathyroil Cells, J. of Clinical Endocrinology and Metabolism, 74(2), 1992.
Barr, et al., Efficient Catheter-Mediated Gene Transfer into the Heart using Replication-Defective Adenovirus, Gene Therapy, 1(1):51-58, 1994.
Blaese, et al., T Lymphocyte-Directed Gene Therapy for ADA SCID: Initial Trial Results After 4-Years, Science, 270, 1995.
Bordignon, et al., Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA Immunodeficient Patients, Science, 270, 1995.
Bouaziz, et al., Vascular Endothelial Cell Responses to Different Electrically Charged Poly (Vinylidene Fluoride) Supports Unfer Static and Oscillating Flow Conditions, Biomaterials, 1996 Elsevier Science Ltd. Great Britain, 18:107 112, 1997.
Bouaziz, et al., Effect of Constant and Modulated Electrical Charges Applied to the Culture Material on PG12 and TXA2 Secretion by Endothelial Cells, Biomaterials 16(9), 1995.
Bugiardini, et al., Relation of Severity of Symptoms to Transient Myocardial Ischemia and Prognosis in Unstable Angina, American College of Cardiology, JAAC 25(3):597-604, 1995.
Chiu, et al., Cellular Cardiomyoplasty: Myocardial Regeneration with Satellite Cell Implantation, Ann. Thoracic Surgery, 60:12-18, 1995.
Chowdhury, Long-Term Improvement of Hypercholesterolemia After Ex Vivo Gene Therapy in LDLR-Deficient Rabbits, Science, 254, 1991.
Dichek, et al., Enhanced In-Vivo Antithrombotic Effects of Endothelial Cells Expressing Recombinant Plasminogen Activators Transduced with Retroviral Vectors, Basic Science Reports, AHA, Inc., 1996.
Dunn, et al., Seeding of Vascular Grafts with Genetically Modified Endothelial Cells, Secretion of Redombinant TPA Results in Decreased Seeded Cell Retention In-Vitro and In-Vivo, Basic Science Reports, AHA, Inc., 1960.
Ekhterae, et al., Retroviral Vector-Mediated Transfer and Expression of Human Tissue Plasminogen Activator Gene in Human Endothelial and Vascular Smooth Muscle Cells, Jobs Research Laboratories, Dept. of Surgery and the Univ of Michigan, Ann arbor, The Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter, 1995.
Fletcher, et al., Acute Myocardiol Infarction, Pathophysiology of Heart Disease, Chap. 7:113-129.
French, et al., Direct In-Vivo Gene Transfer into Porcine Myocardium Using Replication-Deficient Adenoviral Vectors, Circulation, 90:2414-2424, 1994.
Gal, et al., Direct Myocardial Transfection in two Aminal Models, Laboratory Investigation., 68(1):18-25, 1993.
Gillis, et al., Secretion of Prostacyclin, Tissue Plasminogen Activator and its Inhibitor by Cultured Adult Human Endothellal Cells Grown on Different Matrices, W.B. Saunders Company, Ltd., 1996.
Grossman, et al., Sucessful Ex Vivo Gene Therapy Directed to Liver in a Patient with Famllial Hypoercholesterolaemia, Nature Genetics, 6, 1994.
Innis, et al., Key Concepts for PCR, edds. PCR Strategies, Academic Press, New York, 1995.
Johns, et al., Adr\enovirus-Mediated Expression of a Voltage-Gated Potassium Channel In-Vitro (Rat Cardiac Myocytes) and In-Vivo (Rat Liver), Journal of Clinical Investigation., 96:1152-1158, 1995.
Kao, et al., Cellular Cardiomyoplasty: Myocardial Repair with Cell Implantation, Landes Bioscience, Chap. 5 & 8, 1997.
Klug, et al., DNA Synthesis and Multinycleation in Embryonic Stem Cell-Derived Cardiomyocytes, American Journal of Physiology, 269(6):1913-1921, part 2 of 3 parts.
Koh, et al., Stable Fetal Cardiomyocyte Grafts in the Hearts of Dystrophic Mice and Dogs, Journal of Clinical Investigation, 96:2034-2042, 1995.
Kohn, et al., Engraftment of Gene-Modified Umbilical Card Blood Cells in Neonates with Adenosine Deaminase Deficiency, Nature Medicine, 10, 1995.
Leor, et al., Adenovirus-Mediated Gene Transfer into Infarcted Myocardium: Feasibility, Timing, and Location of Expression, J. of Molecular and Cellular Cardiology, 28(10):2057-2067, 1996.
Levin, et al., Protein Kinase C and the Stimulation of Tissue Plasminogen Activator Release from Human Endothelial Cells, J. of Biolopgical Chemistry by the American Society for Biochemistry and Molecular Biology, Inc., 264(27):16030-16036, 1989.
Li, et al., Cardiomyocyte Transplantation Improves Heart Function, Annals of Thoracic Surgery, 60:654-661, 1996.
Mesri, et al., Expression of Vascular Endothelial Growth Factor from a Defective Herpes Simplex Virus Type 1 Amplicon Vector Induces angiogenesis in mice, Circulation Research, 76:161-167. 1995.
Meyle, et al., Fibroblast Anchorage to Microtextured Surfaces, J. of Biomedical Materials Research, 27:1553-1557, 1993.
Murry, et al., Muscle Differentiation During Repair of Myocardial Necrosis in Rats via Gene Transfer with MyoD, J. Clin. Invest., 98:2209-2217, 1996.
Murry, et al., Sheletal Myoblast Transplantation for Repair of Myocardial Necrosis, J. Clin. Invest. 98:2512-2523, 1996.
Nabel, Recombinant Gene Expression In Vivo within Endothelial Cells of the Arterial Wall, Science, 244, 1989.
Nilius, et al., Activation of a C1-Current by Hypotonic Volume Increase in Human Endothelial Cells, The Rockefeller University Press, 103:787-805, 1994.
Olson, Remington: the Science and Practice of Pharmacy (Table of Contents), Remington's Pharmaceutical Sciences, (standard reference text) vol. II.
Parmacek, et al., The Structure and Regulation of Expression of the Murine Fast Skeletal Troponin C Gene, J. Biological Chemistry, 265(26):15970-15976, 1990.
Parmacek, et al., Identification and Characterization of a Cardiac-Specific Transcriptional Regulatory Element in the Slow/Cardiac Troponin C Gene, Molecular and Cellula

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