Method and system for modulation of microbial cell...

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S093450, C435S174000, C435S176000, C435S177000

Reexamination Certificate

active

10436973

ABSTRACT:
A method and a system is disclosed for the modulation of various characteristics of probiotic cells and for the production of probiotics having altered characteristics. Such altered characteristics include increased resistance to various stresses, drugs and chemical agents, as well as aggregation. Such a method and a system are useful for the production of probiotics with altered characteristics, which may for example provide health benefits when present in the gastrointestinal tract of an animal.

REFERENCES:
patent: 6797266 (2004-09-01), Naidu
patent: 2002/0081311 (2002-06-01), Shanahan et al.
patent: 2002/0192202 (2002-12-01), Naidu
patent: 2003/0003107 (2003-01-01), Farmer
patent: 2003/0092163 (2003-05-01), Collins et al.
patent: 2003/0113306 (2003-06-01), Collins et al.
patent: 2004/0197277 (2004-10-01), Gonzales
Lamboley, L. et al. 1997. Continuous mixed strain mesophilic lactic starter productio in supplemental whey permeate medium using immobilized cell technology. Biotechnol. Bioeng. 56(5): 502-516.
Du Toit, M. et al. 1998. A modified continiuos flow culture system for studying microbial interactions related to the gastro-intestional tract: Application of the probiotic organism Enterococcus faecium SF68. Biosci. Microflora 17(1): 41-47.
Durant et al, International J. Food Microbiology, 1997, 38:181-189.
du Toit et al, International J. Food Microbiology, 1998, 40:93-104.
Camelin et al, Biotechnol. Prog., 1993, 9:291-297.
Audet et al, Process Biochemistry, Dec. 1989, pp. 217-226.
Gibson et al, J. Nutr., 2000, 130:391S-395S.
Hong et al, FEMS Microbiology Reviews, 2004, article in press.
Roberfroid, Drug Discovery Today, Dec. 2003, 8/24:1107-1108.
Ostlie et al, International J. Food Microbiology, 2003, 87:17-27.
Ronka et al, International J. Food Microbiology, 2003, 83:63-74.
Yuki et al, International J. Food Microbiology, 1999, 48:51-57.
Holzapfel et al, International J. Food Microbiology, 1998, 41:85-101.
Cho et al, Current Microbiology, Apr. 2000, 40/4:257-263 Abstract only.
Velazquez et al, J. Food Protection, 1997, 60/5:537-543 Abstract only.
Saarela et al, J. Biotechnology, 2000, 84:197-215.
Doleyres et al, International Dairy Journal, 2005, 15:973-988.
Cachon, R. et al. 1998. The comparative behavior ofLactococcus lactisin free and immobilized culture processes. J. Biotechnol. 63: 211-218.
Fortin, C. et al. 1990. Effect of immobilization in calcium alginate gel beads on regulation of protease production byMyxococcus xanthuscells. Physiology of immobilized cells, Proceedings of an International Symposium held at Wagegingen, The Netherlands, Dec. 10-13, 1989: 415-419
Jouenne, T. et al. 1994. Agar-entrapped bacteria as an in vitro model of biofilms and their susceptibility to antibiotics. FEMS Microbiol. Letters 119: 237-242.
Keweloh, H. et al. 1990. Phenol-induced membrane changes in free and immobilizedEscherichia coli. Appl. Microbiol. Biotechnol. 33:66-71.
Keweloh, H. et al. 1990. Phenol tolerance of immobilized bacteria. Physiology of immobilized cells, Proceedings of an International Symposium held at Wagegingen, The Netherlands, Dec. 10-13, 1989: 545-550.
Krisch, J. et al. 1997. Ethanol and acetic acid tolerance in free and immobilized cells ofSaccharomyces cerevisiaeandAcetobacter aceti. Biotechnol. Lett. 19: 525-528.
Krishnan, S. et al. 2001. Physiological and morphological changes in immobilizedL. PlantarumNCIM 2084 cells during repeated batch fermentation for production of lactic acid. Food Biotechnol. 15: 193-202.
Lamboley, L. et al. 1999. Long-Term Mechanical and Biological Stability of an Immobilized Cell Reactor for Continuous Mixed-Strain Mesophilic Lactic Starter Production in Whey Permeate. Biotechnol. Prog. 15: 646-654.
Lamboley, L. et al. 1997. Continuous Mixed Strain Mesophilic Lactic Starter Production in Supplemented Whey Permeate Medium Using Immobilized Cell Technology. Biotechnol. Bioeng. 56: 502-516.
Lamboley, L. et al. 2001. Effect of Inoculum Composition and Low KCI Supplementation on the Biological and Rheological Stability of an Immobilized-Cell System for Mixed mesophilic Lactic Starter Production. Biotechnol. Prog. 17: 1071-1078.
Tannock, G.W. et al. 2000. Analysis of the Fecal Microflora of Human Subjects Consuming a Probiotic Product ContainingLactobacillus rhamnosusDR20. Appl. Env. Microbiol. 66: 2578-2588.
Teixeira de Mattos, M.J. et al. 1994. Metabolic shift analysis at high cell densities. FEMS Microbiol. Rev. 14: 21-28.
Trauth, E. et al. 2001. Resistance of Immobilized Lactic Acid Bacteria to the Inhibitory Effect of Quarternary Ammonium Sanitizers. Lebensm.-Wiss.u.-Technol.34: 239-243.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method and system for modulation of microbial cell... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and system for modulation of microbial cell..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and system for modulation of microbial cell... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3893762

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.