Method and system for identifying splice variants of a gene

Details Method and system for identifying splice variants of a gene Method and system for identifying splice variants of a gene

2008-03-04

2008-03-04

Zeman, Mary K. (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C702S020000, C703S011000, C707S793000, C435S006120, C536S024300

Reexamination Certificate

active

10146720

ABSTRACT:
A method and system for identifying mRNA present in a sample. A splice variant technique selects a set of possible exon-exon junctions based on exons of expected mRNA transcripts. The splice variant technique then selects indicator polynucleotides for the exon-exon junctions and detects the expression level of the indicator polynucleotides in the sample. The splice variant technique then may use a mathematical algorithm to identify possible splice variants in the sample from the observed expression levels.

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