Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-09-29
1996-07-30
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 536 2431, 536 2433, 204461, 204466, 204612, 204616, 382128, 382129, 382140, C12Q 168, C12P 1934, C07H 2104
Patent
active
055410677
ABSTRACT:
The present invention pertains to a process which can be fully automated for accurately determining the alleles of STR genetic markers. More specifically, the present invention is related to performing PCR amplification on locations of DNA, labelling the PCR products, converting the labels into a signal, removing a reproducible PCR stutter pattern from the signal by means of a computational device, and then determining the genotype of the location of the DNA. An amplification can include multiple locations from the DNA of one or more individuals. The invention also pertains to genetics applications and systems which can effectively use this genotyping information.
REFERENCES:
patent: 5161204 (1992-11-01), Hutcheson et al.
patent: 5273632 (1993-12-01), Stockham et al.
Perlin et al. "Toward Fully Automated Genotyping: Genotyping Microsatellite Markers By Deconvolution", Am. J. Hum. Genetics 57:119-21 1995.
Schwartz et al. "Fluorescent mulitplex linkage analysis and carrier detection for Duchenne/Becker Muscular Dystrophy" Am J. Human Genet. 51: 721-729, 1992.
Jones W. Gary
Rees Dianne
Schwartz Ansel M.
LandOfFree
Method and system for genotyping does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and system for genotyping, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and system for genotyping will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1657702