Method and system for genotyping

Details Method and system for genotyping Method and system for genotyping

1996-10-21

2000-04-25

Myers, Carla J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435912, 204456, 204461, 382128, 382129, 382199, 382276, 382279, 382280, C12Q 168, C12P 1934, G06K 920

Patent

active

060542683

ABSTRACT:
The present invention pertains to a process which can be fully automated for accurately determining the alleles of genetic markers. More specifically, the present invention is related to performing PCR amplification on locations of DNA to generate a reproducible pattern, labeling the PCR products, converting the labels into a signal, operating on the signal, and then determining the genotype of the location of the DNA. An amplification can include multiple locations from the DNA of one or more individuals. The invention also pertains to genetics applications and systems which can effectively use this genotyping information.

REFERENCES:
patent: 5161204 (1992-11-01), Hutcheson et al.
patent: 5273632 (1993-12-01), Stockham et al.
Schwartz et al. Am. J. Human Genetics 51: 721-729, 1992.
McConkey et al. In Human Genetics: The Molecular Revolution, Jones and Bartlett Publishess, pp 92-112, 1993.

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