Method and system for differential diagnosis based on clinical a

Details Method and system for differential diagnosis based on clinical a Method and system for differential diagnosis based on clinical a

1993-04-28

1995-10-31

Huntley, David M.

Boots, shoes, and leggings

395 11, 395 21, G06F15900

Patent

active

054635489

ABSTRACT:
A method and system for computer-aided differential diagnosis of diseases, and in particular, computer-aided differential diagnosis using neural networks. A first embodiment of the neural network distinguishes between a plurality of interstitial lung diseases on the basis of inputted clinical parameters and radiographic information. A second embodiment distinguishes between malignant and benign mammographic cases based upon similar inputted clinical and radiographic information. The neural networks were first trained using a hypothetical data base made up of hypothetical cases for each of the interstitial lung diseases and for malignant and benign cases. The performance of the neural network was evaluated using receiver operating characteristics (ROC) analysis. The decision performance of the neural network was compared to experienced radiologists and achieved a high performance comparable to that of the experienced radiologists. The neural network according to the invention can be made up of a single network or a plurality of successive or parallel networks. The neural network according to the invention can also be interfaced to a computer which provides computerized automated lung texture analysis to supply radiographic input data in an objective and automated manner.

REFERENCES:
patent: 4730259 (1988-03-01), Gallant
patent: 4839807 (1989-06-01), Doi et al.
patent: 4912647 (1990-03-01), Wood
patent: 4941122 (1990-07-01), Weidemann
patent: 5023045 (1991-06-01), Watanabe et al.
patent: 5046019 (1991-09-01), Basehore
Journal of Clinical Engineering, vol. 16, No. 6, Dec. 1986, Miller et al. "A Case Study in the Use of an Advanced Expert System Tool or Diagnosis of Cardiovascular Disease", pp. 449-452.
IEEE Int. Conf. on Neural Networks, Jul. 1988, Cat. No. 88CH2632-8, Egbert et al. "Preprocessing of Biomedical Images for Neurocomputer Analysis", pp. 561-568.
IEEE Int. Conf. on Neural Networks, Jul. 1988, Saito et al., "Medical Diagnostic expert System Based on PDP Model", pp. 255-262.
IEEE Int. Conf. on Neural Networks, Jul. 1988, Bounds et al., "A Multi-Layer Perceptron Network for the Diagnosis of Low Back Pain", pp. 481-489.
Neural Networks, vol. 3, No. 5, 1990, "A Comparison of Neural Networks and Other Pattern Recognition Approaches to the Diagnosis of Low Back Disorders", pp. 583-591.
Neurocomputing Applications: Sensor Processing, Control, and Data Analysis, Hecht-Nelson, 1990 Addison-Wesley Pub. Co., pp. 317 to 357.
INNC 90 Paris Conference, 9-13 Jul. 1990, Anthony et al., "The use of neural networks in classifying lung scintigrams" (abstract only).
Radiology, vol. 177, No. 3, Dec. 1990, Asada et al., "Potential Usefulness of an Artificial Network for Differential Diagnosis of Interstitial Lung diseases" (abstract only).
Conference: Computer Assisted Radiology: Proceedings of the Int. Symposium CAR '91, Jul. 1991, Penedo, "A multi-layered neural network for the recognition of lung nodules on digital chest radiographs" (abstract only).
Conference: The 13th Annual symposium on computer Application in Medical Care, Cat. No. 89tH0286-5, Nov. 1989, Meistrell et al., "Evaluation of neural network performance by receiver operating characteristic analysis" (abstract only).
Am J Clin Pathol, 1991, Dawson et al., "Nuclear Grading of Breast Carcinoma . . . " (abstract only).
Neurol Networks, vol. 3, No. 5, 1990, Silverman, "Image Processing and Pattern Recognition in Ultrasonograms by Backpropagation" (abstract only).
Conference: scientific assembly annual meeting of the radiological society of North America, Chicago, 1987, Oldham et al,. "Neural Network Recognition of Mammographic Lesions" (abstract only).
Conference: Proceedings of the Annual Int. Conf. of the IEEE Eng. in Medicine and Biology Society, Cat. No. 89CH2770-6, 1989, Cohen et al., "Combination of a neural network model and a rule-based expert system to determine efficacy of medical testing procedures" (abstract only).

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