Radiant energy – Invisible radiant energy responsive electric signalling – Infrared responsive
Patent
1994-08-26
1996-04-02
Fields, Carolyn E.
Radiant energy
Invisible radiant energy responsive electric signalling
Infrared responsive
25033911, 2503418, G01N 2117, G01N 2125
Patent
active
055043321
ABSTRACT:
A method and system for determining the homogeneity of one or more components of a mixture of ingredients, especially, is presented. Most importantly, it can be used to determine homogeneity of a tabletted mixture of the produced pharmaceuticals, including active and inactive ingredients. The method and system monitor the pharmaceutical material during tablet manufacture as a powder mix, granular mix and compressed tablets. This system uses near infrared technology for analyzing the uniformity and mass balance of the pharmaceutical mixture to control the tablet manufacturing process. As part of the system and method, a NIR spectral library, consisting of a pharmaceutical materials spanning the normal process range for is developed. Assessment of uniformity is accomplished by comparison of future production with the library of acceptable material.
REFERENCES:
patent: 2650307 (1953-08-01), Koppius
patent: 4640614 (1987-02-01), Roberts et al.
patent: 4742228 (1988-05-01), Bischoff
patent: 4883963 (1989-11-01), Kemeny et al.
patent: 4963745 (1990-10-01), Maggard
patent: 4975581 (1990-12-01), Robinson et al.
patent: 5046846 (1991-09-01), Ray et al.
patent: 5099123 (1992-03-01), Harjunmaa
patent: 5145785 (1992-09-01), Maggard et al.
patent: 5187368 (1993-02-01), Galante et al.
patent: 5223714 (1993-06-01), Maggard
patent: 5223715 (1993-06-01), Taylor
patent: 5305076 (1994-04-01), Inoue et al.
patent: 5406084 (1995-04-01), Tobler et al.
Plugge et al., J. of Pharm. & Biomed. Anal., vol. 11, No. 6, pp. 435-442 (1993).
Baxter Mark A.
Buchanan Bruce R.
Duff Andy
Richmond Eric W.
Thornton Samuel A.
Bigley Francis P.
Daniel Mark R.
Fields Carolyn E.
Glick Edward J.
Merck & Co. , Inc.
LandOfFree
Method and system for determining the homogeneity of tablets does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and system for determining the homogeneity of tablets, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and system for determining the homogeneity of tablets will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2018146