Method and system for determining native neurological...

Data processing: generic control systems or specific application – Specific application – apparatus or process – Robot control

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C700S257000, C424S199100, C424S205100, C424S229100, C600S409000, C600S544000, C600S545000, C701S023000, C324S248000

Reexamination Certificate

active

06516246

ABSTRACT:

BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to methods for determining the dominant cerebral hemisphere of a subject and in particular, to novel methods and systems for recognizing and implementing a subject's dominant hemisphere for therapeutic and other uses.
2. Description of the Related Art
Understanding how a primate or human brain functions in making decisions and implementing voluntary and involuntary movements has been studied and analyzed for many years. At one time, there was a theory that there is contralaterality of motor control in humans. However, substantial clinical evidence suggests that the contralaterality theory is problematic. Thus, during surgical procedures and other therapeutic treatments involving the brain, errors in judgment in terms of which lobe of the cerebrum controls which movements can be made by the attending physician since a person's actual “wiring” for either left or right handedness might have been reversed by environmental factors, but the fact remains that their actual dominant hemisphere is as genetically predisposed.
That around 90% of the population is right handed and the remainder is not, is an agreed upon statistic. Yet there is no technical definition of handedness, only arbitrary inventories. But even those have been disputed on several grounds, including that a person's stated manual preference does not always, or even often, match their observed performance; taking us back to where we started. Clearly a technical definition of handedness is needed to escape from the dilemma thus posed as well as a development of an understanding of the neural underpinning of the prior observations is needed in the art. Such an understanding provides the framework for software to be programmed in the control of robotics or prosthesis, and additionally will be useful to surgeons during procedures when it is highly advantageous to know for a certainty which cerebral hemisphere of the subject being treated is dominant.
SUMMARY OF THE INVENTION
In accordance with the present invention, there is provided a method and system for determining the dominant cerebral hemisphere of a subject. There is further provided a method and system for using information obtained regarding hemisphere dominance for programming electronic devices such as robots, prostheses, as well as methods for using such information during treatment and surgical procedures in order to obtain superior function and/or movement when there is injury or disease to an area of the brain. The present invention employs a vectorial view of the role of callosum in the underpinning lateralities of speech and handedness, and as such, provides a technical definition of handedness (i.e., which hemisphere of the cerebrum is dominant in a particular individual subject). This technical definition is then used to completely accurately replicate or predict voluntary and involuntary movements of the subject and this information, in turn, can be utilized in the field of prosthetics and robotics in order to obtain more accurate depiction of brain function and hence, more authentic replication of movement.
Additional objects, features and advantages of the invention will be set forth in the description which follows, and in part, will be obvious from the description, or may be learned by practice of the invention. The objects, features and advantages of the invention may be realized and obtained by means of the instrumentalities and combination particularly pointed out in the appended claims.


REFERENCES:
patent: 4859587 (1989-08-01), Roizman
patent: 5713354 (1998-02-01), Warden
patent: 5840040 (1998-11-01), Altschuler et al.
patent: 5853733 (1998-12-01), Cochran et al.
patent: 5928648 (1999-07-01), Cochran
patent: 5961982 (1999-10-01), Cochran
patent: 5965138 (1999-10-01), Cochran et al.
patent: 6120773 (2000-09-01), Roizman
patent: 6169981 (2001-01-01), Werbos
patent: 6171239 (2001-01-01), Humphrey
patent: 6183753 (2001-02-01), Cochran et al.
Johan Wessberg et al., “Real-time prediction of hand trajectory by ensembles of cortical neurons in primates”, Nature, vol. 408, Nov. 16, 2000, pp. 361-365.
John K.Chapin et al, “Real-time control of a robot arm using simultaneously recorded neurons in the motor cortex”, Nature Neuroscience, vol. 2, No. 7, Jul. 1999, pp. 664-670.
Jerome N. Sanes, “The Relation Between Human Brain Activity and Hand Movements”, NeuroImage 11, 2000, pp. 370-374.
“A spelling device for the paralysed”, Nature, Mar. 25, 1999, pp. 297-298.
Bagrat Amirikian et al, “Cortical Populations and Behaviour: Hebb's Thread”, Canadian Journal of Experimental Psychology, 1999, 53:1, pp 21-34.
“Neuronal Coding and Robotics”, Science, vol. 237, No. 4812, Jul. 17, 1987, pp 300-301.
Carlo A. Marzi, “The Poffenberger paradigm: A first, simple behavioural tool to study interhemispheric transmission in humans”, Brain Research Bulletin, vol. 50, Nos. 5/6, 1999, pp. 421-422.
D. Chawla et al., “The physiological basis of attentional modulatino in extrastriate visual areas”, Nature Neuroscience, vol. 2, No. 7, Jul. 1999.
Chapin, et al, J Neurosci Methods, Dec. 15, 1999, Pub Med abstract relating to “Principal component analysis of neuronal ensemble activity reveals multidimensional somatosensory representations”, 2 pages.
Nicolelis et al, J Neurophysiol Sep. 1997, Pub Med abstract relating to “Neonatal whisker removal reduces the discrimination of tactile stimuli by thalamic ensembles in adult rats”, 2 pages.
Chapin, Curr Opin Neurol Dec. 2000, Pub Med abstract relating to “Neural prosthetic devices for quadriplegia”, 1 page.
Chapin, Prog Brain Res, 2000, Pub Med abstract relating to “Impact of neuroprosthetic applications on functional recovery”, 1 page.
Nicolelis et al, Science Jun. 2, 1995, Pub Med abstract relating to “Sensorimotor encoding by synchronous neural ensemble activity at multiple levels of the somatosensory system”, 1 page.
Chapin, Electroencephalogr Clin Neurophysiol Suppl 1996, Pub Med abstract relating to “Neural network mechanisms of oscillatory brain states: characterization using simultaneous multi-single neuron recordings”, 1 pg.
Nicolelis et al., J Neurophysiol 1996, Pub Med abstract relating to “Active tacile exploration influences the functional maturation of the somatonsensory system” 2 pages.
Nicolelis et al., Nat Neurosci, Nov. 1998, Pub Med abstract relating to “Simulaneous encoding of tactile information by three primate cortical areas”, 1 page.
Zeck et al., Proc Natl Acad Si USA Aug. 28, 2001, abstract relating to “Noninvasive neuroelectronic interfacing with synaptically connected snail neurons immobilized on a semiconductor chip”.
Iacoboni et al., Parallel visuomotor processing in teh split brain: Cortico-subcortical interactions, 2000, Internet, pp. 759-769.*
DiCarlo et al., Structure of receptive fields in area 3b of primary somatosensory cortex in the alert monkey, 1998, Internet, pp. 2626-2645.*
Ackerman et al., Hemispheric lateralization of teh neural eecoding of the temporal speech features: a whole-head magnetencephalography study. no date, Internet, p. 1.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method and system for determining native neurological... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and system for determining native neurological..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and system for determining native neurological... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3151735

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.