Method and system for determination of instantaneous and average

Details Method and system for determination of instantaneous and average Method and system for determination of instantaneous and average

1989-10-27

1992-09-22

Shaw, Dale M.

Boots, shoes, and leggings

250303, 128654, 128691, G06F 1500

Patent

active

051502925

ABSTRACT:
A method and system for quantitation of blood flow rates by using digital subtraction angiographic (DSA) images, wherein the spatial shift of the distribution of contrast material injected into an opacified vessel in the acquired angiographic images is analyzed as a bolus of the contrast material proceeds through the vessel. In order to determine the distance that the bolus travels between image acquisitions, there is obtained from the DSA images the distribution of vessel contrast along the length of the vessel, called and "distance-density" curve. The distance that the contrast material travels during the time between two images acquisitions is determined by means of cross correlation of the two respective distance-density curves. The flow rate between the image acquisitions is calculated by multiplying this distance by the frame rate and the vessel cross-sectional area which is estimated from the vessel size assuming a circular cross section. Thus, for high frame-rate acquistions, instantaneous blood flow rates can be determined. The method and system are particularly useful for measurement of pulsatile blood flow rates.

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Hoffmann et al. "Automated tracking of the vascular tree in DSA images using a double-squate-box region-of-search algorithm" SPIE vol. 626 Medicine XIV/PACS IV, pp. 326-333 (1986).
Fujita et al. "Image feature analysis and computer-aided diagnosis in digital radiography" Med. Phys. 14(4), Jul./Aug. 1987 pp 549-556.

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