Surgery – Diagnostic testing – Cardiovascular
Reexamination Certificate
2006-10-10
2006-10-10
Pezzuto, Robert E. (Department: 3766)
Surgery
Diagnostic testing
Cardiovascular
C600S521000
Reexamination Certificate
active
07120485
ABSTRACT:
There are many different serious cardiac arrhythmias. The present invention uses measurements of RR intervals (interbeat intervals) to detect, in particular but not exclusively, atrial fibrillation of a patient. Atrial fibrilation is a serious ailment in which the heartbeat is generally rapid and irregular. Probability density histograms of ΔRRs (difference between two successive RR intervals) collected during atrial fibrillation of a plurality of subjects are used as a template for the detection of atrial fibrillation. In one implementation, there are 16 standard probability density ΔRRs histograms every 50 ms of mean RR interval of a certain number of beats, where the mean RR interval ranges from 350 ms to 1149 ms. Similarity between the standard probability density histograms and a test density probability histogram of ΔRRs of a patient is estimated by the Kolmogorov-Smirnov test. If the test density histogram is not significantly different from the standard density histogram, atrial fibrillation is detected.
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Glass Leon
Tateno Katsumi
Bertram Eric D.
Girma Wolde-Michael
Soldner Michael C.
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