Method and system for cellular transplantation in the spinal...

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

Reexamination Certificate

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C604S500000

Reexamination Certificate

active

07666177

ABSTRACT:
The present invention provides a method for treating an injury of a spinal cord of a patient The method includes implanting a therapeutic substance in the spinal cord under indirect visualization. The indirect visualization may be provided by an endoscope, and the therapeutic substance may include cells. The present invention also provides a device for treating an injury of the spinal cord. The device includes skin visualization means for visualizing the spinal cord through a skin puncture, and injection means for injecting a therapeutic substance into the spinal cord.

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“Schwann cell genetically modified to secrete human BDNF promote axonal regowth across transected adult rat spinal cord”. Phililppe Menei et al., European Journal of Neuroscience, vol. 10, pp. 607-621, 1998.
Casas, CE, EJ Owen, Oliveira M, Guest JD: Endoscopic Transplantation into the conus medullaris. Soc. Neurosci Abstr. 2002 852.8. Nov. 2002.
Cellular transplantation into the spinal cord using an endoscopic technique. C Casas, E Owen, J Guest. Presented at the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves, Orlando, FL, Feb. 2002.

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