Method and system for automatically creating...

Details Method and system for automatically creating... Method and system for automatically creating...

2007-04-24

2007-04-24

Allen, Marianne P. (Department: 1647)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C702S020000, C435S006120

Reexamination Certificate

active

09354500

ABSTRACT:
A method and system are disclosed for automatically creating crosstalk-corrected data of a microarray utilizing calibration dye spots each of which comprises a single pure dye. A microarray scanner, such as a confocal laser microarray scanner, generates dye images, each of which contains at least one of the calibration dye spots for each of the output channels of the scanner. For each of the calibration dye spots, an output of each of the output channels is measured to obtain output measurements. A set of correction factors is computed from the output measurements to correct the data subsequently gathered from the microarray scanner. In other words, the correction factors are applied to quantitation or measurement data obtained from microarray images which contain spots having dyes of known or unknown excitation or emission spectra to obtain crosstalk-corrected data.

REFERENCES:
patent: 5578832 (1996-11-01), Trulson et al.
patent: 5631734 (1997-05-01), Stern et al.
patent: 5702887 (1997-12-01), Law et al.
patent: 5728528 (1998-03-01), Mathies et al.
patent: 5733729 (1998-03-01), Lipshutz et al.
patent: 5795716 (1998-08-01), Chee et al.
patent: 5804386 (1998-09-01), Ju
patent: 5807522 (1998-09-01), Brown et al.
patent: 5814454 (1998-09-01), Ju
patent: 5821993 (1998-10-01), Robinson
patent: 5853992 (1998-12-01), Glazer et al.
patent: 6040138 (2000-03-01), Lockhart et al.
patent: 6075613 (2000-06-01), Schermer et al.
patent: 6225636 (2001-05-01), Ginestet
patent: 6245507 (2001-06-01), Bogdanov
patent: 6251601 (2001-06-01), Bao et al.
patent: 6320196 (2001-11-01), Dorsel et al.
patent: WO 98/15649 (1998-04-01), None
patent: WO 98/17992 (1998-04-01), None
Shalon, D. et al., Genome Research, 6(7):639-45, Jul. 1996.
Schena et al.; Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray; Science; vol. 270; Oct. 20, 1995; pp. 467-470.

Affiliated with

Also associated with

Rating

Method and system for automatically creating... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and system for automatically creating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and system for automatically creating... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3781881