Method and system for assisting in diagnosing irritable...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007100, C436S001000, C436S501000, C436S518000, C424S009100, C424S520000, C530S300000, C530S350000

Reexamination Certificate

active

07943328

ABSTRACT:
The present invention provides methods, systems, and code for accurately classifying or diagnosing a sample from an individual as an IBS sample. The methods and systems of the present invention are useful for ruling out one or more diseases or disorders that share a similar clinical presentation as IBS followed by identifying (i.e., ruling in) IBS using statistical algorithm(s) and/or empirical data. In particular, the methods and systems of the present invention use a first combination of learning statistical classifier systems to rule out IBD with an accuracy of greater than about 90% and a second combination of learning statistical classifier systems to rule in IBS in a non-IBD sample with an accuracy of greater than about 80%.

REFERENCES:
patent: 5750355 (1998-05-01), Targan et al.
patent: 5830675 (1998-11-01), Targan et al.
patent: 5858688 (1999-01-01), Haskill et al.
patent: 6074835 (2000-06-01), Braun et al.
patent: 6218129 (2001-04-01), Walsh et al.
patent: 6630444 (2003-10-01), Schwartz et al.
patent: 6656474 (2003-12-01), Cedarbaum
patent: 6986995 (2006-01-01), Rose et al.
patent: 7048906 (2006-05-01), Lin et al.
patent: 7138237 (2006-11-01), Targan et al.
patent: 7192724 (2007-03-01), Boone et al.
patent: 2002/0025348 (2002-02-01), Basu et al.
patent: 2002/0052007 (2002-05-01), Chang et al.
patent: 2002/0168698 (2002-11-01), Boone et al.
patent: 2003/0077246 (2003-04-01), Welcher et al.
patent: 2003/0082652 (2003-05-01), Holten-Andersen et al.
patent: 2003/0091549 (2003-05-01), Collins et al.
patent: 2003/0124617 (2003-07-01), Gram et al.
patent: 2003/0133875 (2003-07-01), Kelly
patent: 2003/0143548 (2003-07-01), Camilleri et al.
patent: 2003/0153495 (2003-08-01), Lichenstein et al.
patent: 2003/0157061 (2003-08-01), Bennett
patent: 2003/0211106 (2003-11-01), Tornetta et al.
patent: 2003/0215450 (2003-11-01), Blake et al.
patent: 2004/0043931 (2004-03-01), Hersberg et al.
patent: 2004/0077020 (2004-04-01), Mannick et al.
patent: 2004/0106778 (2004-06-01), Fagan et al.
patent: 2004/0122787 (2004-06-01), Avinash et al.
patent: 2004/0137074 (2004-07-01), Vidal et al.
patent: 2004/0213788 (2004-10-01), Sweet et al.
patent: 2004/0229783 (2004-11-01), Pothoulakis et al.
patent: 2004/0235960 (2004-11-01), Burns et al.
patent: 2005/0004155 (2005-01-01), Boyd et al.
patent: 2005/0009766 (2005-01-01), Brantl
patent: 2005/0031583 (2005-02-01), Grewal
patent: 2005/0065327 (2005-03-01), Monk et al.
patent: 2005/0100531 (2005-05-01), Bienenstock
patent: 2005/0107399 (2005-05-01), Boman et al.
patent: 2005/0130189 (2005-06-01), Pasricha et al.
patent: 2005/0136495 (2005-06-01), Boone et al.
patent: 2005/0187176 (2005-08-01), Bates et al.
patent: 2005/0220909 (2005-10-01), Theoharides
patent: 2005/0282840 (2005-12-01), Ross et al.
patent: 2006/0014224 (2006-01-01), Brunner et al.
patent: 2006/0058365 (2006-03-01), Kohn et al.
patent: 2006/0079442 (2006-04-01), Ilan et al.
patent: 2006/0121015 (2006-06-01), Collins et al.
patent: 2006/0189528 (2006-08-01), Roberts et al.
patent: 2006/0211752 (2006-09-01), Kohn et al.
patent: 2006/0217307 (2006-09-01), Takashi et al.
patent: 2006/0233743 (2006-10-01), Kelly
patent: 2006/0258604 (2006-11-01), Strober et al.
patent: 2006/0275210 (2006-12-01), Rosen et al.
patent: 2007/0003518 (2007-01-01), Atkinson et al.
patent: 2007/0015773 (2007-01-01), Bergeron et al.
patent: 2007/0020660 (2007-01-01), Burczynski et al.
patent: 2007/0269804 (2007-11-01), Liew et al.
patent: 2008/0085524 (2008-04-01), Lois
patent: 2008/0166719 (2008-07-01), Lois
patent: 2010/0094560 (2010-04-01), Lois et al.
patent: 2010/0222228 (2010-09-01), Thielemans et al.
patent: 1 439 393 (2004-07-01), None
patent: 1 439 393 (2004-07-01), None
patent: WO 99/64627 (1999-12-01), None
patent: WO 00/00608 (2000-01-01), None
patent: WO 00/00608 (2000-01-01), None
patent: WO 00/41707 (2000-07-01), None
patent: WO 00/41707 (2000-07-01), None
patent: WO 01/11334 (2001-02-01), None
patent: WO 01/11334 (2001-02-01), None
patent: WO 03/029423 (2003-04-01), None
patent: WO 03/029423 (2003-04-01), None
patent: WO 03/068170 (2003-08-01), None
patent: WO 03/087830 (2003-10-01), None
patent: WO 03/087830 (2003-10-01), None
patent: WO 2004/009797 (2004-01-01), None
patent: WO 2004/009797 (2004-01-01), None
patent: WO 2004/022727 (2004-03-01), None
patent: WO 2004/085677 (2004-10-01), None
patent: WO 2004/085677 (2004-10-01), None
patent: WO 2004/096853 (2004-11-01), None
patent: WO 2005/009339 (2005-02-01), None
patent: WO 2005/009339 (2005-02-01), None
patent: WO 2005/029091 (2005-03-01), None
patent: WO 2005/029091 (2005-03-01), None
patent: WO 2005/068655 (2005-07-01), None
patent: WO 2005/068655 (2005-07-01), None
patent: WO 2006/048698 (2006-05-01), None
patent: WO 2006/057027 (2006-06-01), None
patent: WO 2006/085075 (2006-08-01), None
patent: WO 2006/085075 (2006-08-01), None
patent: WO 2007/011674 (2007-01-01), None
U.S. Appl. No. 11/565,544, Lois et al.
Farrell, R.J., “Epidermal Growth Factor for Ulcerative Colitis,”The New England Journal of Medicine, Jul. 24, 2003, vol. 349, No. 4, pp. 395-397.
Katsuta, T. et al., “Interleukin-8 and SDF1-α mRNA Expression in Colonic Biopsies From Patients With Inflammatory Bowel Disease,”The American Journal of Gastroenterology, 2000, vol. 95, No. 11, pp. 3157-3164.
Nielsen, O.H. et al., “Intestinal Interleukin-8 Concentration and Gene Expression in Inflammatory Bowel Disease,”Scand. J. Gastroenterol., 1997, vol. 32, pp. 1028-1034.
Nielsen, O.H. et al., “Rectal Dialysate and Fecal Concentrations of Neutrophil Gelatinase- , Associated Lipocalin, Interleukin-8, and Tumor Necrosis Factor-α in Ulcerative Colitis,”The American Journal of Gastroenterology, 1999, vol. 94, No. 10, pp. 2923-2928.
Seth, R. et al., “Correlation Between Interleukin-8 (IL8) mRNA Levels and Histological Findings in Inflammatory Bowel Disease,” Jan. 4-6, 1995, p. 101A (Meeting Abstract).
Restriction Requirement in U.S. Appl. No. 11/838,810 dated Apr. 8, 2010, pp. 1-11.
Restriction Requirement in U.S. Appl. No. 11/838,810 dated Jul. 15, 2010, pp. 1-7.
Office Action in U.S. Appl. No. 11/838,810 dated Oct. 27, 2010, pp. 1-21.
Restriction Requirement in U.S. Appl. No. 11/841,660 dated May 6, 2010, pp. 1-11.
Office Action in U.S. Appl. No. 11/841,660, dated Oct. 13, 2010, pp. 1-16.
Communication Relating to the Results of the Partial International Search mailed on Jul. 17, 2008, for PCT Application No. PCT/US2007/075976, filed on Aug. 15, 2007, 3 pages.
Barbara, G. et al.; “New pathophysiological mechanisms in irritable bowel syndrome,”Ailment Pharmacol Ther.; 2004; vol. 20, Suppl. 2, pp. 1-9.
Curnow, S.J. et al., “Multiplex Bead Immunoassay Analysis of Aqueous Humor Reveals Distinct Cytokine Profiles in Uveitis,”Investigative Ophthalmology&Visual Science, Nov. 2005, vol. 46, No. 11, pp. 4251-4259.
Delafoy, L., et al., “Interactive involvement of brain derived neurotrophic factor, nerve growth factor, and calcitonin gene related peptide in colonic hypersensitivity in the rat,”Gut, 2006; vol. 55, pp. 940-945.
Dinan, T.G. et al., “Hypothalamic-Pituitary-Gut Axis Dysregulation in Irritable Bowel Syndrome: Plasma Cytokines as a Potential Biomarker?”Gastroenterology, Feb. 1, 2006, vol. 130, No. 2, pp. 304-311.
Drossman, D.A., “What Does the Future Hold for Irritable Bowel Syndrome and the Functional Gastrointestinal Disorders?”Journal of Clinical Gastroenterology, May/Jun. 2005, vol. 39, No. 4, Suppl. 3, pp. S251-S256.
Kane, S.V., “Fecal Lactoferrin Is a Sensitive and Specific Marker in Identifying Intestinal Inflammation,”American Journal of Gastroenterology, 2003, vol. 98, No. 6, pp. 1309-1314.
Thierry, P. et al., “Impact of Fatigue in Irritable Bowel syndrome: Role of Plasma Leptin,”Gastroenterology AGA Abstracts, Apr. 1, 2005, vol. 128, No. 4, Suppl. 2, Abstract No. W1488, p. A-623.
Wiley, S.R. et al., “TWEAK, a Member of the TNF Superfamily, is a Multifunctional Cytokine That Binds the TweakR/Fn1

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method and system for assisting in diagnosing irritable... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and system for assisting in diagnosing irritable..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and system for assisting in diagnosing irritable... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2697648

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.