Method and reagent for the specific determination of LDL in seru

Details Method and reagent for the specific determination of LDL in seru Method and reagent for the specific determination of LDL in seru

1996-02-20

1998-09-08

Ceperley, Mary E.

Chemistry: analytical and immunological testing

Lipids, triglycerides, cholesterol, or lipoproteins

436 13, 436815, 436825, G01N 3392

Patent

active

058044507

ABSTRACT:
The invention relates to a method and reagent for the specific determination of the LDL fraction in the presence of other serum lipoproteins by adding a water soluble polymeric LDL-aggregating agent and a zwitterionic and/or non-ionic detergent. The LDL aggregate is determined in a direct turbidimetric measurement. Preferred LDL-aggregating agents are polyanions having a branched structure with acid groups, particularly branched alkane sulfonic acid groups as side branches. Preferred detergents are those known as "Zwittergent".

REFERENCES:
patent: 5411870 (1995-05-01), Law et al.

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