Method and reagent for the detection of fibrin monomer

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 13, G01N 3354, C12Q 156

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044290403

ABSTRACT:
The present invention provides a process for the detection or determination of fibrin monomer in biological fluids, wherein the sample fluid is incubated with hydrophobic latex and the agglutination determined.
The present invention also provides a reagent for the detection or determination of fibrin or fibrin monomer in biological fluids, wherein it contains hydrophobic latex.

REFERENCES:
patent: 3088875 (1963-05-01), Fisk
patent: 4090846 (1978-05-01), Buck
patent: 4181636 (1980-01-01), Fischer
patent: 4208185 (1980-06-01), Sawai et al.
Wilner et al., J. Lab. Clin. Med., vol. 97, No. 3, pp. 403-411 (Mar. 1981).
Nihei et al., "Fibrin Degradation Product (FDP) Determination in Urine by FDP Latex Test-U", Chem. Abstracts, vol. 93, No. 3, p. 337, (1980), abst. No. 22064w.
Someraro, "Fibrinogen, Fibrinopeptide A and Fibrin Monomers," Acta Clinica Belgica, vol. 32, No. 6 (1977) pp. 380-385.
Nihei et al., "Fibrin Degradation Product (FDP)"Determination in Urine" by FDP Latex Test-U, Shindan to Chiryo, vol. 68, No. 3 (1980), pp. 558-560.

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