Method and products for human papillomavirus detection

Details Method and products for human papillomavirus detection Method and products for human papillomavirus detection

1992-01-15

1994-09-13

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

536 2432, 435 6, 5303871, C12Q 170, C12Q 168, C07H 2100, C07K 1500

Patent

active

053468112

ABSTRACT:
The present invention provides a Human Papillomavirus (HPV) detection method, the results capable of being read on specimen slides through in situ hybridization techniques. The method is based on a pair of consensus polynucleotide probes which hybridize type-specifically with clinically important HPV viral types and is capable of distinguishing between malignant and benign HPV viruses. Compositions of the polynucleotide probes in detectably labeled form are also a part of the invention. For correlation of the present method with known polymerase chain reaction (PCR) detection of HPV, a PCR assay is described.

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