Method and product for the treatment of gastric disease

Drug – bio-affecting and body treating compositions – Lymphokine

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424 87, 5303884, 5303871, 5303891, A61K 39395, C07K 1528, C07K 1500

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active

052600572

ABSTRACT:
This invention describes a product obtained from the isolation and concentration of specific immunoglobulins (antibodies) derived from the mammary secretions of cows immunized with Helicobacter pylori. The product is useful in preparing formulations for the treatment and/or prevention of gastric diseases.

REFERENCES:
patent: 3128230 (1964-04-01), Heinbach
patent: 3984539 (1976-10-01), Khuow et al.
patent: 3992521 (1976-11-01), LeMinor
patent: 4051235 (1977-09-01), Plymate
patent: 5143727 (1992-09-01), Ebina
"Bovine Milk Immunoglobulins (Ig), Their Possible Utilization in Industrially Prepared Infant's Milk Formulae", Hilpert et al, XII Symposium of the Swedish Nutritional Foundation, pp. 182-196 (1977).
"Treatment of Infantile E. coli Gastroenteritis with Specific Bovine Anti E. coli Milk Immunoglobulins", Mietens et al., European Journal of Pediatrics, 132:239-252 (1979).
"Prevention of Rotavirus Infection by Cow Colostrum Containing antibody Against Human Rotavirus", Ebina et al, The Lancet, pp. 1029-1030, Oct. 29, 1983.
Laboratory Techniques in Biochemistry and Molecular Biology, Monoclonal Antibody Technology, edited by Burdon et al, pp. 1-32 (1984).
"Prevention of rotavirus infection by oral administration of cow colostrum containing anti human rotavirus antibody", Ebina et al., Medical Microbiology & Immunology, 174:177-185 (1985).
"Monoclonal antibodies directed against the flagella of Campylobacter jejuni", Newell, J. Hyg. Camb., 96:131-141 (1986).
"Protection against Campylobacter jejuni Infection in Suckling Mice by Anti-Flagellar Antibody", Ueki et al., Microbiol. Immunol., 31:(12)1161-1171 (1987).
Campylobacter pylori, Raws & Tytgat editors, pp. 89-103 and 138-139 (1989).

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