Method and pharmaceutical preparations for reducing the activity

Details Method and pharmaceutical preparations for reducing the activity Method and pharmaceutical preparations for reducing the activity

1995-09-22

1998-10-27

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Hydrocarbon doai

A61K 3101

Patent

active

058279008

ABSTRACT:
A method of reducing the activity of a cell comprises administering to the cell of a subject in need thereof, directly or systemically, a cell activity-reducing effective amount of lycopene. Pharmaceutical composition are derscribed, for inhibiting the growth of cancer cells, comprising as an active ingredient a cancer cell growth-inhibiting effective amount of lycopene.

REFERENCES:
patent: 5008295 (1991-04-01), Nishino et al.
Cancer Letters, 48(2), 135-142(1989) "Inhibition of Growth--" by C.J. Wang, et al.
Proc. Nat. Sci. Counc. ROC, 13(3), 176-183(1989) "Inhibitory Effects--" by C.J. Wang, et al.
Clinical Chemistry, 37(6), 1056(1991) Abstract "Lyncopene Inhibits--" by Countryman, C., et al.
Free Radical Research Communications, 16(6), 401-8(1992) "Carotene-oxygen radical interactions" by Conn, PF, et al.
Pharmacology 4(6), 334-340(1970), "Action of lycopene in the experimental gastric ulcer", MILANI, C., et al.
Cancer Research, 52(20), 5707-12(1992), "Carotenoids Up-regulate--", Zhang, Li-Xin, et al.

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