Chemistry: analytical and immunological testing – Biospecific ligand binding assay
Patent
1983-04-26
1985-12-10
Marantz, Sidney
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
422 57, 435 7, 436518, 436527, G01N 3354, G01N 2154
Patent
active
045580120
ABSTRACT:
A member for detecting and/or measuring the level of concentration of a chemical substance in a medium comprises a non-metal substrate bearing a dielectric layer. A detection reactant which is capable of reacting with the substance to be detected is put on the dielectric layer and the assembly is put into the medium to be investigated, whereupon an optically detectable layer of the substance to be detected is formed on the detection reactant. The substrate is light-absorbing and one or more further dielectric layers is or are disposed between the substrate and the first-mentioned dielectric layer thereon, the thickness of the further dielectric layer or layers being such that the overall assembly comprising all the dielectric layers, the layer of detection reactant thereon and the layer of substance to be detected, is reflection-reducing in respect of non-monochromatic light which is reflected at the surface of the substrate on which the array of layers is disposed, in the wavelength range of from 525 to 600 nm.
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Nygren B. Hakan
Sandstrom E. Torbjorn
Stenberg Johan E.
Stiblert Lars B.
Foulke Cynthia Lee
Marantz Sidney
Sagax Instrument AB
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