Method and means for allergy diagnosis

Details Method and means for allergy diagnosis Method and means for allergy diagnosis

1989-08-10

1992-03-24

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

436527, 436541, 436804, 436807, 436811, C12Q 170, G01N 33552, G01N 33538

Patent

active

050988310

ABSTRACT:
The histamine in a sample is determined by contacting the sample with a histamine binding agent, such as glass, which has been treated, e.g., with a polar organic polymer, to reduce the affinity of the agent for an interfering component of the sample while substantially retaining the agent's histamine-binding capacity. Such an agent facilitates determination of histamine in whole blood samples. Preferably, the agent is provided as a conglomerate of histamine-binding bodies, such as glass fibers, in a binder. Preferred binders are polyvinyl acetate, a vinyl acetate/ethylene copolymer, and polyvinyl alcohol or combinations thereof.

REFERENCES:
patent: 4550085 (1985-10-01), Skov et al.
patent: 4869875 (1989-09-01), Skov et al.
Skov, Norn and Weeke, "A New Method for Detecting Histamine Release", Agents and Actions, 14:414-416 (1984).
Verburg and Henry, "Binding of Histamine by Glass Surfaces", Agents and Actions, 14:633-636 (1984).
Trade brochure distributed by H. Lundbeck Diagnostics A/S, of Copenhagen, Denmark, the brochure is undated except for a code on the last page stating "HLD 87 Olgivy & Mather Direct".
Mosbech and Skov, "House Dust Mite-Induced Histamine Release from Washed Blood Cells", Allergy, 42:553-555 (1987).
Nolte, Schlotz and Skov, "A New Glass Microfiber-Based Histamine Analysis for Allergy Testing in Children", Allergy, 42:366-373 (1987).
Skov, Mosbech, Norn and Weeke, "Sensitive Glass Microfiber-Based Histamine Analysis for Allergy Testing in Washed Blood Cells", Allergy, 40:213-218 (1985).
Chemical Abstracts, vol. 66, 1967, 48961d.

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