Method and kit for sample adherence to test substrate

Details Method and kit for sample adherence to test substrate Method and kit for sample adherence to test substrate

1988-05-10

1991-06-18

Lacey, David L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

436174, 436175, 435810, C12Q 168, G01N 100, G01N 128

Patent

active

050249339

ABSTRACT:
Disclosed is an improvement relating to adhesion of samples onto a surface for nucleic acid hybridization assay to detect a target polynucleotide. In one aspect, the invention provides a method of adhering a tissue, cell or other target polynucleotide-containing sample to a substrate under nucleic acid hybridization assay compatible conditions. In another aspect, the method comprises a hybridization assay procedure. Also disclosed are kits for performance of such procedures.

REFERENCES:
patent: 4668637 (1987-05-01), Guesdon et al.
patent: 4908404 (1990-03-01), Benedict et al.
Kaleem et al., Nature, vol. 325, pp. 328-329, 1987.
Thiebaut et al., PNAS, vol. 84, pp. 7735-7738, Nov. 1987.
Engel, American Biotechnology Laboratory, Jun. 1988.

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