Chemistry: analytical and immunological testing – Immunochemical pregnancy determination
Patent
1982-08-18
1985-04-02
Marantz, Sidney
Chemistry: analytical and immunological testing
Immunochemical pregnancy determination
422 61, 436 65, 436519, 436808, 436814, 436818, 436827, G01N 3354, G01N 3358, G01N 3376
Patent
active
045088292
ABSTRACT:
Method and kit for pregnancy detection adapted for self-performance. Urine to be tested is contacted with a lectin substrate being lectin bound to a solid support and capable of binding HCG. After separation of the lectin substrate from the urine the substrate is contacted with a liquid color reagent comprising a colored carrier material and anti-HCG antibodies bound thereto. If after separation of the colored reagent from the substrate the latter remains colored, the subject is pregnant, while lack of color indicates non-pregnancy. A preferred color reagent comprises killed and stained Staphylococci bacteria. There is also provided a kit for self-performance of the method comprising at least one column packed with a lectin substrate and adapted for the controlled passage of liquid therethrough, and a color reagent.
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P. G. Natali et al., Jour. of Immunological Methods, 25, 255-264, (1979).
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Pompecki et al., Cancer Research, 41 (1), (1981), pp. 1905-1909.
Guesdon et al., Journal of Immunological Methods, 39, (1980), pp. 1-13.
Marantz Sidney
Teva Pharmaceutical Industries Ltd.
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