Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-10-28
1996-12-24
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435 792, 436518, G01N 33543
Patent
active
055872948
ABSTRACT:
The present invention relates to methods for measuring endogenous cytokines in blood. The method accurately measures the cytokines in the blood in the presence of substances that bind the cytokines thereby causing the measurement of the cytokines by conventional methods to give inaccurate results. The present invention also includes the non-invasive measurement of cytokines in biological fluids such as saliva and nasal secretions. Finally, the present invention allows one to monitor the level of cytokines in the blood during treatment of a human or animal with cytokines.
REFERENCES:
patent: Re31006 (1982-08-01), Schuurs et al.
patent: Re32696 (1988-06-01), Schuurs et al.
patent: 3654090 (1972-04-01), Schuurs et al.
patent: 3839153 (1974-10-01), Schuurs et al.
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 4016043 (1977-04-01), Schuurs et al.
patent: 4020151 (1977-04-01), Bolz et al.
patent: 4185084 (1980-01-01), Mochida et al.
patent: 4271140 (1981-06-01), Bunting
patent: 4376110 (1983-03-01), David et al.
patent: 4486530 (1984-12-01), David et al.
patent: 4496654 (1985-01-01), Katz et al.
patent: 4594326 (1986-06-01), Wade
patent: 4798207 (1989-01-01), Wade
patent: 4863726 (1989-09-01), Stevens et al.
Khan et al., "Human testis cytosol and ovarian follicular fluid contain high amounts of interleukin-1-like factor(s),"0 Molecular and Cellular Endocrinology, No. 58, pp. 221-230 (1988).
Wade et al., "Time-Integrated Measurementof Cortocosteroids in Saliva by Oral Diffusion Sink Technology," Clinical Chemistry, vol. 37, pp. 1-7 (1991).
Charon et al., "Increased Thymocyte-Activating Factor in Human Gingival Fluid During Gingival Inflammation," Infection and Immunity, vol. 38, No. 3, pp. 1190-1195 (Dec. 1982).
Oppenheim et al., "Evidence for an In Vivo Inflammatory Role of Interleukin 1 (IL 1)," Transplantation Proceedings, vol. XIV, Nov. 3, pp. 553-555 (Sep. 1982).
Westacott et al., "Synovial fluid concentration of five different cytokines in rheumatic diseases," Ann. Rheum. Dis., vol. 49(a), pp. 676-681 (1990).
Tamatani et al., "Existence of both IL-1a and .beta. in normal amniotic fluid: unique high molecular weight form IL-1.beta.," Immunology, vol. 65, pp. 337-342 (1988).
Kimball et al., "Interleukin 1 Activity in Normal Human Urine," The Journal of Immunology, vol. 133, No. 1, pp. 256-260 (Jul. 1964).
Eastgate et al., "Correlation of Plasma Interleukin 1 Levels with Disease Activity in Rheumatoid Arthritis," The Lancet, pp. 706-709 (Sep. 24, 1988).
Cannon et al., "Increased Plasma Interleukin-1 Activity in Women After Ovulation," Science, vol. 227, pp. 1247-1249 (Mar. 8, 1985).
Maury et al., "Serum Immunoreactive Interlleukin-1 in Renal Transplant Recipients," Transplantation Proceedings, vol. XIX, No. 5, pp. 4349-4350 (Oct. 1987).
Cannon et al., "Endogenous Pyrogen Activity in Human Plasma After Exercise," Science, vol. 220, pp. 617-619 (May 6, 1983).
Waage et al., "The Complex Pattern of Cytokines in Serum From Patients with Meningococcal Septic Shock: Association between Interleukin 6, Interleukin 1, and Fatal Outcome," J. Exp. Med., vol.169, pp. 333-338 (Jan. 1989).
Moldawer et al., "Circulating interleukin 1 and tumor necrosis factor during inflammation," The American Physiological Society, pp. R922-R928 (1987).
Miyai, "Enzyme Immunoassay System--Schematic Representation," Chapter IV, pp. 123-135.
Vilja et al., "A Rapid and Sensitive Non-Competitive Avidin-Biotin Assay for Lactoferrin," Journal of Immunological Methods, vol. 76, pp. 73-83 (1985).
Goldstein et al., "A competitive enzyme-linked immunoassay (ELISA) for the measurement of soluble human interleukin-2 receptor (IL-2R, Tac protein)," Journal of Immunological Methods, vol. 107, pp. 103-109 (1988).
Fuccillo, "Application of the Avidin-Biotin Technique in Microbiology," BioTechniques, vol. 3, No. 3, pp. 494-501 (1985).
Voller et al., "Enzyme immunoassays with special reference to ELISA techniques," Journal of Clinical Pathology, vol. 31, pp. 507-520 (1978).
Voller, "The Enzyme Linked Immunosorbent Assay (ELISA)", Diagnostic Horizons, vol. 2, No. 1, pp. 1-7 (Feb. 1978).
Jansson et al., "A biotin-labelled antigen radioimmunoassay (BILA) for antibodies to membrane antigens useful for monoclonal antibody screening," Journal of Immunological Methods, vol. 115, pp. 219-226 (1988).
Maldiney et al., "A biotin-avidin-based enzyme immunoassay to quantify three phytohormones: auxin, abscisic acid and zeatin-riboside," Journal of Immunological Methods, vol. 90, pp. 151-158 (1986).
Wagener et al., "Monoclonal antibodies for carcinoembryonic antigen and related antigens as a model system: determination of affinities and specificities of monoclonal antibodies by using biotin-labelled antibodies and avidin as precipitating agent in a solution phase immunoassay," The Journal of Immunology, vol. 130, No. 5, pp. 2302-2307 (May 1983).
Shiosaka et al., "A new method for producing a specific and high tire antibody against glutamate using colloidal gold as a carrier," Brain Res., vol. 382, pp. 399-403 (1986).
Novick, et al., Journal of Exp. Med., vol. 170, pp. 1409-1414 (1989).
Honda et al., The Journal of Immunology, vol. 148, No. 7, pp. 2175-2180, (1992).
Fanslow et al., Cytokine, vol. 2, No. 6, pp. 398-401, (1990).
Novick et al., Journal of Chromatography, vol. 510, pp. 331-337, (1990).
Fanslow et al., Science, vol. 248, pp. 739-741 (1990).
Svenson et al., Scand. J. Immunol, vol. 29, pp. 489-492 (1989).
Svenson et al., Scand J. Immunol, vol. 32, pp. 695-701 (1989).
Hansen et al., Scand J. Immunol, vol. 33, pp. 777-781 (1991).
Caruso et al., The Journal of Immunology, vol. 144, No. 2, pp. 685-690 (1990).
Cannon et al., Lymphokine Research, vol. 7, No. 4, 457-467 (1988).
Capper et al., Cytokine, vol. 2, No. 3, 182-189 (1990).
Mae et al., Lymphokine Cytokine and Research, vol. 10, No. 1, 61-68 (1991).
Interleukin 1 .beta. in Human Plasma: Optimization of Blood Collection, Plasma Extraction, and Radioimmunoassay Methods, Research Reports, vol. 7, No. 4, pp. 457-467 (1988).
Tumor Necrosis Factor (TNFa) Binding Protein: Interference in Immunoassays of TNAa, Kidney International, vol. 40, pp. 1166-1170 (1991).
Paciotti, G. F. et al., "Novel Enzyme Immunoassays for the Detection of the Cytokines Interleukin 1a and Interleukin 2 in the Circulation of Normal Subjects: 24-Hour Profiles," Progress in NeuroEndocrinImmunology, vol. 5, No. 1, pp. 21-30 (1992).
Mygind, N. et al., l"Immunological Barriers in the Nose and Paranasal Sinuses," Acta Otolaryngol (Stockh), vol. 103, pp. 363-368 (1987).
Endres, E. et al., "In vitro production of IL 1.beta., IL 1 <<, TNF and IL2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation," Eur. J. Immunol., vol. 19, pp. 2327-2333 (1989).
Matsuda, T. et al., "Establishment of an interleukin 6(IL6)/B cell stimulatory factor 2-dependant cell line and preparation of anti-IL 6 monoclonal antibodies," Eur. J. Immunol., vol. 18, pp. 951.956 (1988).
Lisi, Peter J. et al., "Development and Use of a Radioimmunoassay for Human Interleukin-1.beta." Lymphokine Research, vol. 6, No. 3, pp. 229-244 (1987).
Michie, Hamish R. et al., "Detection of Circulating Tumor Necrosis Factor After Endotoxin Administration", The New England Journal of Medicine, vol. 318, No. 23, pp. 1481-1486 (Jun. 9, 1988).
Endres, Stefan et al., "Measurement of Immunoreactive Interleukin-1.beta. from Human Mononuclear Cells: Optimization of Recovery, Intrasubject Consistency, and Comparison with Interleukin-1a and Tumor Necrosis Factor", Clinical Immunology and Immunopathology, vol. 49, pp. 424-438 (1988).
Paciotti, G. F. et al., "Determination of the 24-hour profiles of circulating IL-1-alpha and IL-2 levels in normals," Lymphokine Research, vol. 9, No. 4, pp. 594-95 (Oct. 1, 1990).
van der Meer, Jos W. M. et al., "Concentrations of Immunoreactive Human Tumor Necrosis Factor Alpha Produced by Human Mononuclear Cells in Vitro,"Journal of Leukocyte Biology, vol. 43, pp. 216-223 (1988).
Paciotti, G. F. et al., "Novel Enzyme Immunoassays for the Detection of the Ctytokines Interleukin 1.
Paciotti Giulio F.
Tamarkin Lawrence
Assay Research, Inc.
Housel James C.
Tanigawa Gary
LandOfFree
Method and kit for measuring endogenous cytokines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and kit for measuring endogenous cytokines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and kit for measuring endogenous cytokines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1178076