Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1996-04-01
1998-04-21
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 536 231, 536 243, 536 2433, 536 266, C12Q 168, C12P 1934, C07H 2102, C07H 2104
Patent
active
057416494
ABSTRACT:
A method and kit for detecting breast cancer cells is disclosed, which is not only as convenient and noninvasive as conventional cytological examination, but also is more accurate and objective than cytological examination. The invention establishes a method for detecting breast cancer cells, wherein the method judges cells examined to be breast cancer cells when aneusomy is detected on 1) either chromosome 1 or chromosome 11 or both, 2) either chromosome 1 or chromosome 17 or both or 3) at least any one of chromosomes 1, 11 and 17 of the cell sample.
REFERENCES:
patent: 5545527 (1996-08-01), Stevens et al.
Sato et al, "Allelotype of Breast Cancer: Cumulative Allele Losses Promote Tumor Progression in Primary Breast Cancer", Cancer Res. 50, pp. 7184-7189, 1990.
Takita et al, "Correlation of Loss of Alleles on the Short Arms of Chromosomes 11 and 17 with Metastasis of Primary Breast Cancer to Lymph Nodes", Cancer Res. 52, pp. 3914-3917, 1992.
Bieche et al, "Two Distinct Regions Involved in 1p Deletion in Human Primary Breast Cancer", Cancer Res. 53 pp. 1990-1994, 1993.
Winqvist et al, "Refinement of Regional Loss of Heterozygosity for Chromosome 11p15.5 in Human Breast Tumors", Cancer Res., pp. 4486-4488, 1993.
Chen et al, "Deletion of Two Separate Regions on Chromosome 3p in Breast Cancers", Cancer Res. 54, pp. 3021-3024, 1994.
Waye et al, "Chromosone-Specific Alpha Satellite DNA from Human Chromosome 1: Hierarchical Structure and Genomic Organization of a Polymorphic Domain Spanning Several Hundred Kilobase Pairs of Centromic DNA", Genomics 1, pp. 43-51, 1987.
Inazawa et al, "Assignment of the Human Granulocyte Colony-Stimulating Factor Receptor Gene (CSF3R) to Chromosome 1 at Region p 35-p 34.3", Genomics 10, pp. 1075-1078, 1991.
Inazawa et al, "High-Resolution Cytogenetic Mapping of 342 New Cosmid Markers Including 43 RFLP Markers on Human Chromosome 17 by Fluorescence in SituHybridization", pp. 153-162, 1993.
Jones et al, "Detection of Loss of Heterozygosity at the Human TP53 Locus Using a Dinucleotide Repeat Polymorphism", Genes, Chromosomes and Cancer, pp. 89-90, 1992.
Isomura et al, "Detailed Analysis of Loss of Heterozygosity on Chromosome Band 17p13 in Breast Carcinoma on the Basis of a High-Resolution Physical Map With 29 Markers", Genes, Chromosomes and Cancer, pp. 173-179, 1994.
Strawbridge et al, "Role of Cytology in Management of Lesions of the Breast", Surg. Gynecol. & Obstet., vol. 152, No. 1 pp. 1-7, 1981.
Miki et al, "A Strong Candidate for the Breast and Ovarian Cancer Susceptibilty Gene BRCA 1", Science, vol. 266, pp. 66-71, 1994.
Tokino et al, "Isolation and Mapping of 62 New RFLP Markers on Human Chromosome 11", Am. J. Hum. Genet., vol. 48, pp. 258-268, 1991.
Tanigami et al, "Mapping of 262 DNA Markers into 24 intervals on Human Chromosome 11", Am. J. Hum. Genet., vol. 50, pp. 56-64, 1992.
Takahashi et al, "R-banding and nonisotopic in situ hybridization: precise localization of the human type II collagen gene (COL 2A1)",Hum. Genet. vol 86, pp. 14-16, 1990.
Gyapay et al, "The 1993-94 Genethon human genetic linkage map". Nature Genetics, vol. 7, 1994, pp. 247-249.
Cooke et al, "Cloning of human satellite III DNA: different components are on different chromosomes", Nucleic Acids Research, vol. 6, No. 10, 1979, pp. 3177-3197.
Waye et al, "Organization and evolution of alpha satellite DNA from human chromosome 11", Chromosoma, vol. 95, pp. 182-188.
Waye et al, "Structure, Organization, and Sequence of Alpha Satellite DNA from Human Chromosome 17: Evidence for Evolution by Unequal Crossing-Over and an Ancestral Pentamer Repeat Shared with the Human X Chromosome", Mol. and Cell. Bio. p. 3156-3165, 1986.
"Molecular Cloning: A Laboratory Manual", Cosmid Vectors, pp. 3.27-3.53 2nd ed., 1989.
Pinkel et al, "Cytogenic analysis using quantitative, high-sensitivity, fluorescence hybridization", Proc. Natl. Acad. Sci. USA, vol. 83, pp. 2934-2938, 1986.
Harrison et al, "Chromosome 1 Aneusomy, Identified by Interphase Cytogenics, in Mammographically Detected Ductal Carcinoma in situof the Breast", Journal of Pathology, vol. 175, pp. 303-309, 1995.
Verdoodt et al, "Improved detection of DNA aneuploidy in primary breast cancer using quantitative DNA image analysis in combination with fluorescent in situhybridization technique", Hist. J., vol. 27. pp. 79-88. 1995.
Murphy et al, Interphase Cytogenetic Analysis of erbB2 an topoll.alpha. Co-amplification in Invasive Breast Cancer and Polysomy of Chromosome 17 in Ductal Carcinoma in situ, Int. J. Cancer, vol. 64, pp. 18-26, 1995.
Devilee et al, "Detection of Chromosome Aneuploidy in Interphase Nuclei from Human Primary Breast Tumors Using Chromosome-specific Repetitive DNA Probes", pp. 5825-5830, 1988.
Loupart et al. "Confirmation of the copy number of chromosome 1 in interphase nuclei from paraffin sections of breast tumours by fluorescence in situhybridization", Chromosome Res., vol. 3, 410-416, 1995.
Dhingra et al, "Chromosome in situhybridization on formalin-fixed mammary tissue using no-isotopic, non-fluorescent probes: technical considerations and biological implications", Breast Cancer Research and Treatment, vol. 23, pp. 201-210, 1992.
Micale et al, "Chromosomal Aneuploidy in Proliferative Breast Disease", Human Pathology, vol. 25, No. 1, pp. 29-35, 1994.
Waldeman et al. Proc. Annu Meet. Am Assoc Cancer Research 32: pp.A179, 1991.
Deville et al. Cancer Research 48: 5825-5830 1988.
Daikin Co., Ltd.
Jones W. Gary
Rees Dianne
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