Method and kit for detecting antibodies specific for HLA and/or

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 721, 435 795, 435975, 436518, G01N 33543

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active

055145574

ABSTRACT:
The present invention is directed to determining the presence of antibodies from a patient's blood which are specific for HLA Class I antigens and/or platelet glycoproteins. The invention provides for a method and kit for diagnosing platelet disorders in an easy to use format. The method and kit employ a solid support, such as microtiter plate wells, that are coated with the HLA and glycoprotein antigens. A sample of the patient's blood is added to the coated wells and allowed to react, then spectrophotometric detection of antibodies provides diagnostic quantitation.

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